Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q90405
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q90405-F1 | Predicted | AlphaFoldDB |
No variants for Q90405
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q90405 | |||||
No associated diseases with Q90405
16 regional properties for Q90405
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | Major vault protein, N-terminal | 54 - 115 | IPR002499-1 |
| repeat | Major vault protein, N-terminal | 116 - 166 | IPR002499-2 |
| repeat | Major vault protein, N-terminal | 167 - 219 | IPR002499-3 |
| repeat | Major vault protein, N-terminal | 220 - 274 | IPR002499-4 |
| repeat | Major vault protein, N-terminal | 276 - 324 | IPR002499-5 |
| repeat | Major vault protein, N-terminal | 325 - 381 | IPR002499-6 |
| repeat | Major vault protein, N-terminal | 382 - 434 | IPR002499-7 |
| domain | Major vault protein, shoulder domain | 509 - 658 | IPR021870 |
| domain | Major vault protein repeat domain 3 | 457 - 518 | IPR040989 |
| domain | Major vault protein repeat domain 2 | 48 - 103 | IPR041134-1 |
| domain | Major vault protein repeat domain 2 | 271 - 317 | IPR041134-2 |
| domain | Major vault protein repeat domain 4 | 377 - 435 | IPR041136 |
| domain | Major vault protein repeat domain | 111 - 151 | IPR041139-1 |
| domain | Major vault protein repeat domain | 164 - 203 | IPR041139-2 |
| domain | Major vault protein repeat domain | 217 - 258 | IPR041139-3 |
| domain | Major vault protein repeat domain | 321 - 366 | IPR041139-4 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEDSIIRIAP | YHYIHVLDQN | TNVARIENGP | KTYIRQDNER | VLFPPERMVT | IPPRHYCVVA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NPVVRDREGM | PVCDGFGQAR | LRHGDREVRL | SQDPFPLYPG | EELGQVATAL | QVVKTNSALH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LQAQLDFEDH | GEKRVAGDEW | LFEGPGTYIP | RTEVVMICWI | NAIVIRHNQG | LRLRARKDTR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DRDGRDRVTG | EEWMVRRVGA | YLPGVYEEVL | DVVNAFILTE | KRALHLRALQ | TVKDMRDRVR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RTGEEWLVTL | AEAEAYVPGV | EEEVVGQVEV | TTLGTRQYCV | VLDPVGADGK | PQLGQKLVVK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GEKSFFLQPG | EHLEAGIQDT | YVLSEEEGLV | LRAVEAFEEK | DEAGKVHCRK | PGDRWMIRGP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VEYVPPVTVE | VLSYRHAIPL | DQNEGIYVRD | LKSGKVRAVI | GESYMLSQDE | ELWEKTLPPN |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VEALLTPDKD | PVLNRNVHQS | EAGHQEEGVK | KRDPTRVVTF | RVPHNAAVQV | YDYSQKSARV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VFGPELVMLE | TDEQLTVLSL | SGGRPKRPGV | IRSLCLLLGP | DFFTDVIVIE | TADHARLQLQ |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LAYNWHFEVK | DRSDPMESAK | VFSVLDFVGD | ACKAIASRIR | GAVASVQFDD | FHKNSSRILR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| AAVFGLDPEL | RVRERLLFPQ | NSLCVTSVDV | HSVEPVDQRT | RDALQRSVQL | AIEITTKSQE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| AAARQEAARL | EQEAKGRLER | QRILDQAESE | RARRELLLLE | ADSTAVESRG | AARAEAESRA |
| 730 | 740 | 750 | 760 | 770 | 780 |
| EASRIEGEGS | VLQAKLKAQA | LDIETEAELE | RLTKAREREL | KYIAEQNRLE | VEKTRQLSEL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| ESRRFQEMVQ | AIGADTIRAI | AESGPELQVK | LLQGLGLNST | LITDGSTPVN | LFSAAKGMLG |
| 850 | |||||
| VPAMSMEHRG | SE |