Q8ZY04

PR
Gene name
gatD
Protein name
Glutamyl-tRNA(Gln) amidotransferase subunit D
Names
Glu-ADT subunit D
Species
Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)
KEGG Pathway
pai:PAE1003
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

27-100 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8ZY04

Entry ID Method Resolution Chain Position Source
AF-Q8ZY04-F1 Predicted AlphaFoldDB

No variants for Q8ZY04

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8ZY04

No associated diseases with Q8ZY04

3 regional properties for Q8ZY04

Type Name Position InterPro Accession
domain Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic 5 - 287 IPR006075
conserved_site Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site 142 - 156 IPR017958
domain Asn/Gln amidotransferase 326 - 473 IPR018027

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
asparaginase activity Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.

3 GO annotations of biological process

Name Definition
cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
regulation of translational fidelity Any process that modulates the ability of the translational apparatus to interpret the genetic code.
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MYKKVRVVLE NGDVFEGVML PPTQFSDSDI VVLKLKNGYN VGFKKGRIKE IVELGEVQTA
70 80 90 100 110 120
PLSAKPMPKI EGEKVWLLAT GGTILSRVDY VTGGVYPTLS VDYLFEVLGG LEAPIEAEEV
130 140 150 160 170 180
TAKFSEDMTP ALWGVIAERV AEAFKKGARG VVVLHGTDTM QYTAAALAFA FKSAPGPIAL
190 200 210 220 230 240
VGAQRSSDRP STDAVLNLKA AIAVTARAPF AESVVVMHKT SGDTVVAVHR GTRVRKMHTS
250 260 270 280 290 300
RRDTFQSINT TPIAEYYPEK ELLQVLTDVY KERGGLDYTA KFEEAVALVK FYPGMHPRLL
310 320 330 340 350 360
EALLEVGMKG VVIEGTGFGH VGEGVLPAVK KLIDAGVIVA MTSQTLYGRV NLYVYRRGRE
370 380 390 400 410
LLSMGVIPLE DMLPETAYAK MSWALANFKR EEVPRVLTTP IAYEMSPRSD PLVFGGL