Q8ZVN0

PR
Gene name
rrp42
Protein name
Exosome complex component Rrp42
Names
Species
Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)
KEGG Pathway
pai:PAE2206
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

62-137 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8ZVN0

Entry ID Method Resolution Chain Position Source
AF-Q8ZVN0-F1 Predicted AlphaFoldDB

No variants for Q8ZVN0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8ZVN0

No associated diseases with Q8ZVN0

2 regional properties for Q8ZVN0

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 38 - 171 IPR001247
domain Exoribonuclease, phosphorolytic domain 2 198 - 260 IPR015847

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasmic exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
rRNA catabolic process The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASISPYGKR FISYLRREQI RRLLATKYRV DGRGPEQTRN VEINVGVVKT ADGSAEVKLG
70 80 90 100 110 120
KTHVVAGVKV GLGQPFPDAP DEGVLVVNAE VLPHASPYTE VGPPDEFAIE LARVVDRGIR
130 140 150 160 170 180
HCGYVDFKKL AVEGGKAYVL WIDLYVINDD GNLIDVANLA SVAALKNTQL PVVVKDEAGV
190 200 210 220 230 240
VKLDRNNKAP LPVDISKAPI AVSVGKIGNV LFLDPTFEEE LSLDGRITFT FSEDKIVAAQ
250 260 270
KTLGYFTQSE IEAALNLALR GRDRLLEALK SALK