Q8ZJ18

PR
Gene name
plsB
Protein name
Glycerol-3-phosphate acyltransferase
Names
GPAT
Species
Yersinia pestis
KEGG Pathway
ypm:YP_0468
EC number
2.3.1.15: Transferring groups other than amino-acyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

773-825 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8ZJ18

Entry ID Method Resolution Chain Position Source
AF-Q8ZJ18-F1 Predicted AlphaFoldDB

No variants for Q8ZJ18

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8ZJ18

No associated diseases with Q8ZJ18

3 regional properties for Q8ZJ18

Type Name Position InterPro Accession
domain Phospholipid/glycerol acyltransferase 281 - 426 IPR002123
domain GPAT/DHAPAT, acyltransferase domain 278 - 479 IPR041728
domain GPAT/DHAPAT, C-terminal domain 434 - 772 IPR045520

Functions

Description
EC Number 2.3.1.15 Transferring groups other than amino-acyl groups
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
glycerol-3-phosphate O-acyltransferase activity Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.
sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity Catalysis of the reaction: hexadecanedioyl-CoA + sn-glycerol 3-phosphate = coenzyme A + 1-C16:0-alpha,omega-dicarboxyl-2-lysophosphatidate.

5 GO annotations of biological process

Name Definition
CDP-diacylglycerol biosynthetic process The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.
fatty acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
glycerol-3-phosphate metabolic process The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
phospholipid biosynthetic process The chemical reactions and pathways resulting in the formation of a phospholipid, a lipid containing phosphoric acid as a mono- or diester.
triglyceride biosynthetic process The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSGWRKIYYK LLNLPLKLLV KSKVIPADPV SELGLDPSRP ILYVLPYNSK ADLLTLRAQC
70 80 90 100 110 120
LAQDLPDPLI PLEIDGVQLP SHVFIENGPR VFRYYVPKQE SVKLFHDYLD LHRNNPALDI
130 140 150 160 170 180
QMLPVSVMFG RSPGREGHGT PHLRVLNGVQ KFFAVLWLGR DSFVRFSTTV SLRRMASEHG
190 200 210 220 230 240
TDKTIAHKLA RVARMHFSRQ RLAAVGPSLP ARQDLFKKLL ASKAIEKAVA DEARSKKISH
250 260 270 280 290 300
EKAQQNAITL MEEIAANFSY EAVRLSDRVL SWTWNRLYQG INVHNAERVR QLAQDGHEIV
310 320 330 340 350 360
YVPCHRSHMD YLLLSYVLYH QGLVPPHIAA GINLNFWPAG PIFRRLGAFF IRRTFKGNKL
370 380 390 400 410 420
YSTVFREYLG ELFTRGYSVE YFVEGGRSRT GRLLEPKTGT LSMTIQAMLR GGTRPITLVP
430 440 450 460 470 480
IYIGYEHVME VGTYAKELRG AIKEKENLLQ MLRGLRKLRN LGQGYVNFGE PLPLTTYLNT
490 500 510 520 530 540
HVPQWRDAID PIEAQRPSWL TPAVNDLANQ IMVRINNAAA ANAMNLCSTA LLASRQRSLT
550 560 570 580 590 600
REQLLEQLDC YLQLMRNAPY AKDTTVPDKT PEELLNHALN MNKFEVEKDT IGDIIILPRE
610 620 630 640 650 660
QAVLMTYYRN NIQHLLILPS LIASMVMYHR RITRTELLHK ISMIYPMLKA ELFLHYSKEQ
670 680 690 700 710 720
LPETLDTLID ELARQQLICD KGSELVLNPA RIRPLQLLAA GVRETLQRYA ITLSLLSATP
730 740 750 760 770 780
SINRGALEKE SRIMAQRLSV LHGINAPEFF DKAVFSTLVA TLREEGYISD SGDAIQEHTL
790 800 810 820
EVYNMLSALM TPEVKLTIES VSMPAETSNQ PEAPETPEPE GKTES