Q8ZHU8
Gene name |
rppH |
Protein name |
RNA pyrophosphohydrolase |
Names |
(Di)nucleoside polyphosphate hydrolase |
Species |
Yersinia pestis |
KEGG Pathway |
ypm:YP_2872 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8ZHU8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8ZHU8-F1 | Predicted | AlphaFoldDB |
No variants for Q8ZHU8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8ZHU8 | |||||
No associated diseases with Q8ZHU8
4 regional properties for Q8ZHU8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | NUDIX hydrolase domain | 6 - 149 | IPR000086 |
| conserved_site | NUDIX hydrolase, conserved site | 38 - 59 | IPR020084 |
| domain | NUDIX hydrolase | 33 - 47 | IPR020476-1 |
| domain | NUDIX hydrolase | 47 - 62 | IPR020476-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| mRNA 5'-diphosphatase activity | Catalysis of the removal of a 5' terminal diphosphate from the 5'-triphosphate end of an mRNA, leaving a 5'-monophosphate end. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA catabolic process | The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIDDDGYRPN | VGIVICNRQG | EVLWARRYGQ | HSWQFPQGGI | NPGETPEQAM | YRELFEEVGL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NKKDVRILAS | TRNWLRYKLP | KRLVRWDTKP | VCIGQKQRWF | LLQLMCNEAE | INMQRSSTPE |
| 130 | 140 | 150 | 160 | 170 | |
| FDGWRWVSYW | YPVRQVVSFK | RDVYRRVMKE | FAATVMPVQE | VAPPRVPPAY | RRKRG |