Q8ZG93

PR
Gene name
pncB
Protein name
Nicotinate phosphoribosyltransferase
Names
NAPRTase
Species
Yersinia pestis
KEGG Pathway
ypm:YP_1180
EC number
6.3.4.21: Other carbon--nitrogen ligases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

105-183 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q8ZG93

Entry ID Method Resolution Chain Position Source
3OS4 X-ray 160 A A/B 1-401 PDB
AF-Q8ZG93-F1 Predicted AlphaFoldDB

No variants for Q8ZG93

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8ZG93

No associated diseases with Q8ZG93

2 regional properties for Q8ZG93

Type Name Position InterPro Accession
domain Nicotinate phosphoribosyltransferase, N-terminal domain 13 - 130 IPR040727
domain Nicotinate/nicotinamide phosphoribosyltransferase 169 - 395 IPR041525

Functions

Description
EC Number 6.3.4.21 Other carbon--nitrogen ligases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

1 GO annotations of molecular function

Name Definition
nicotinate phosphoribosyltransferase activity Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate.

1 GO annotations of biological process

Name Definition
NAD salvage Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTQDASPILT SLLDTDAYKL HMQQAVFHHY RHITVAAEFR CRSDELLGVY ADEIRHQVTL
70 80 90 100 110 120
MGQLALTSDE FIYLSSLPFF QDDYLHWLRD FRFKPEQVSV AVHDGKLDIR IAGLWCEVIM
130 140 150 160 170 180
WEVPLLAVIS EIVHRRRSTQ VTTDQAVQQL RTKLEQFNAL SADIDITHFK LMDFGTRRRF
190 200 210 220 230 240
SREIQHTVVS TLKDEFPYLV GTSNYDLART LALAPVGTQA HEWFQAHQQI SPTLANSQRV
250 260 270 280 290 300
ALQVWLDEYP NQLGIALTDC ITMDAFLRDF DLAFANRYQG LRHDSGDPIE WGEKAIAHYE
310 320 330 340 350 360
KLGIDPMKKV LVFSDNLDLE KALFLYRHFY QRIKLVFGIG TRLTCDIPDV KPLNIVIKLV
370 380 390 400
ECNDKPVAKL SDSPGKTICQ DPAFVDQLRK AFALPLVKKA S