Q8Z6I9
Gene name |
aroH (STY1763, t1228) |
Protein name |
Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive |
Names |
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase |
Species |
Salmonella typhi |
KEGG Pathway |
sty:STY1763 |
EC number |
2.5.1.54: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8Z6I9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8Z6I9-F1 | Predicted | AlphaFoldDB |
No variants for Q8Z6I9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8Z6I9 | |||||
No associated diseases with Q8Z6I9
6 regional properties for Q8Z6I9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Aminoacyl-tRNA synthetase, class II (D/K/N) | 118 - 558 | IPR004364 |
| domain | OB-fold nucleic acid binding domain, AA-tRNA synthetase-type | 18 - 102 | IPR004365 |
| domain | Aminoacyl-tRNA synthetase, class II | 138 - 555 | IPR006195 |
| domain | GAD domain | 307 - 406 | IPR029351 |
| domain | Aspartate-tRNA ligase, type 1, anticodon recognition domain | 2 - 134 | IPR047089 |
| domain | Aspartate-tRNA ligase, type 1, core domain | 138 - 558 | IPR047090 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.54 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3-deoxy-7-phosphoheptulonate synthase activity | Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| aromatic amino acid family biosynthetic process | The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan). |
| cellular amino acid biosynthetic process | The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. |
| chorismate biosynthetic process | The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MNRTDELRTA | RIDSLVTPTE | LAQRYPVSSS | VASHVTDSRR | RIEKILNGED | PRLLVVIGPC |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SIHDLNAAME | YATQLQAQRQ | KHQARLEIVM | RTYFEKPRTV | VGWKGLISDP | DLNGSYRVNH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GLELARRLLL | QVNELGVPTA | TEFLDMVTGQ | FIADLISWGT | IGARTTESQI | HREMASALSC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PVGFKNGTDG | NTRIAVDAIR | ASRASHMFLS | PDKDGQMTIY | QTSGNPYGHI | IMRGGKKPNY |
| 250 | 260 | 270 | 280 | 290 | 300 |
| HAEDIAAACD | TLHEFDLPEH | LVVDFSHGNC | QKQHRRQLDV | CDDICQQIRN | GSTAIAGIMA |
| 310 | 320 | 330 | 340 | ||
| ESFLREGTQK | IISGQPLIYG | QSITDPCLNW | EDTEVLLEKL | AAAVDSRF |