Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8Z2E3

Entry ID Method Resolution Chain Position Source
AF-Q8Z2E3-F1 Predicted AlphaFoldDB

No variants for Q8Z2E3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8Z2E3

No associated diseases with Q8Z2E3

3 regional properties for Q8Z2E3

Type Name Position InterPro Accession
domain LexA repressor, DNA-binding domain 1 - 65 IPR006199
domain Peptidase S24/S26A/S26B/S26C 77 - 192 IPR015927
domain LexA-like 111 - 180 IPR039418

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
lactate transmembrane transporter activity Enables the transfer of lactate from one side of a membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNLWQQNYDP AGNIWLSSLI ASLPILFFFF ALIKLKLKGY VAASWTVVIA LAVALLFYKM
70 80 90 100 110 120
PVDHALASVV YGFFYGLWPI AWIIIAAVFV YKISVKTGQF DIIRSSILSI TPDQRLQMLI
130 140 150 160 170 180
VGFCFGAFLE GAAGFGAPVA ITAALLVGLG FNPLYAAGLC LIVNTAPVAF GAMGIPILVA
190 200 210 220 230 240
GQVTDLDSFE IGQMVGRQLP FLTIIVLFWI MAIMDGWRGV KETWPAVMVA GGSFAIAQYL
250 260 270 280 290 300
SSNFIGPELP DIISSLVSLV CLTLFLKRWQ PVRIFRFGDM GASQVDQTLA RTRYTTGQIV
310 320 330 340 350 360
RAWSPFLFLT ATVTLWSIPP FKALFAPGGA LYDWVINVPV PYLDKLVARM PPVVHEATAY
370 380 390 400 410 420
AAVYKFDWFS ATGTAILFAA LLSIVWLKMK PSAAIQTFGS TLKELALPIY SIGMVLAFAF
430 440 450 460 470 480
ISNYSGLSST LALALAHTGS AFTFFSPFLG WLGVFLTGSD TSSNALFASL QATAAQQIGV
490 500 510 520 530 540
SDVLMVAANT TGGVTGKMIS PQSIAIACAA VGLVGKESDL FRFTVKHSLI FTCMVGVITT
550
LQAYVLTWMI P