Q8Z227

PR
Gene name
malT
Protein name
HTH-type transcriptional regulator MalT
Names
ATP-dependent transcriptional activator MalT
Species
Salmonella typhi
KEGG Pathway
sty:STY4281
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

787-861 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8Z227

Entry ID Method Resolution Chain Position Source
AF-Q8Z227-F1 Predicted AlphaFoldDB

No variants for Q8Z227

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8Z227

No associated diseases with Q8Z227

6 regional properties for Q8Z227

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 6 - 244 IPR003439
domain AAA+ ATPase domain 34 - 221 IPR003593
domain ABC3 transporter permease protein domain 530 - 644 IPR003838
conserved_site ABC transporter-like, conserved site 146 - 160 IPR017871
domain MacB, ATP-binding domain 6 - 222 IPR017911
domain MacB-like periplasmic core domain 275 - 494 IPR025857

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

3 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
positive regulation of DNA-templated transcription Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLIPSKLSRP VRLDHTVVRE RLLAKLSGAN NFRLLLVTSP AGYGKTTLVS QWAAGKNELG
70 80 90 100 110 120
WYSLDEGDNQ QERFASYLIA AIQQATGGHC STSEAMAQKR QYASLTSLFA QLFIELAQWH
130 140 150 160 170 180
RPLYLVIDDY HLITNPVIHD AMRFFLRHQP ENFTLVVLSR NLPQLGIANL RVRDQLLEIG
190 200 210 220 230 240
SQQLAFNHQE AKQFFDRRLS SPIEAAESSR MCDDVAGWAT ALQLIALSAR QNHTSAHHSA
250 260 270 280 290 300
RRLAGINASH LSDYLVDEVL DNVDVSTRHF LLKSAILRSM NDALIVRVTG EENGQMRLEE
310 320 330 340 350 360
IERQGLFLQR MDDTGEWFSY HPLFGSFLRQ RCQWELAAEL PEIHRAAAES WMEQGFPSEA
370 380 390 400 410 420
IHHALAAGDA QMLRDILLNH AWGLFNHSEL ALLEESLKAL PWESLLENPR LVLLQAWLMQ
430 440 450 460 470 480
SQHRYSEVNT LLARAEQEIK GVMDGTLHAE FNALRAQVAI NDGNPEEAER LAKLALDELP
490 500 510 520 530 540
LAWFYSRIVA TSVHGEVLHC KGNLSQSLSL MQQTEQMARH HDVWHYALWS LIQQSEIQFA
550 560 570 580 590 600
QGFLQAAWET QERAFQLIKE QHLEQLPMHE FLVRIRAQLL WAWARLDEAE ASARSGIAVL
610 620 630 640 650 660
STFQPQQQLQ CLTLLVQCSL ARGDLDNARS QLNRLEKLLG NGRYHCDWIS NADKVRVIYW
670 680 690 700 710 720
QLTGDKKSAA NWLRHTPKPA FANNHFLQGQ WRNIARAQIL LGEFEPAEIV LEELNENARS
730 740 750 760 770 780
LRLMSDLNRN LLLLNQLYWQ SGRKNDAQRV LLDALQLANR TGFISHFVIE GEAMAQQLRQ
790 800 810 820 830 840
LIQLNTLPEM EQHRAQRILR YINQHHRHKF AHFDEGFVER LLNHPDVPEL IRTSPLTQRE
850 860 870 880 890 900
WQVLGLIYSG YSNEQIAGEL AVAATTIKTH IRNLYQKLGV AHRQDAVQHA QQLLKMMGYG
V