Q8YXJ6

PR
Gene name
nadB (alr1217)
Protein name
L-aspartate oxidase
Names
LASPO, Quinolinate synthase B
Species
Nostoc sp (strain PCC 7120 / SAG 2582 / UTEX 2576)
KEGG Pathway
ana:alr1217
EC number
1.4.3.16: With oxygen as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

395-474 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8YXJ6

Entry ID Method Resolution Chain Position Source
AF-Q8YXJ6-F1 Predicted AlphaFoldDB

No variants for Q8YXJ6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8YXJ6

No associated diseases with Q8YXJ6

2 regional properties for Q8YXJ6

Type Name Position InterPro Accession
domain FAD-dependent oxidoreductase 2, FAD binding domain 30 - 404 IPR003953
domain Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal 454 - 567 IPR015939

Functions

Description
EC Number 1.4.3.16 With oxygen as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
L-aspartate oxidase activity Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide.
L-aspartate:fumarate oxidoreductase activity Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.

1 GO annotations of biological process

Name Definition
NAD biosynthetic process The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MITHYSLPIT RYPLPRFLTL SQIEFPSQFD VLVVGAGAAG LYTALCLPES LRVGLITKET
70 80 90 100 110 120
VALSASDWAQ GGIAAAIAPN DSPSLHIEDT IQAGAGLCDV AAVEFLAQQA PKCIESLVNL
130 140 150 160 170 180
GVAFDRHGQA LALTLEAAHS RNRVLHAADT TGREVTTTLT DQVLRRPNIQ VIQQALALSL
190 200 210 220 230 240
WLEPETGHCQ GISLFYQGAI TWVRAGAVVL ATGGGGQVFA QTTNPAVSTG DGVAIAWRAG
250 260 270 280 290 300
AILRDLEFVQ FHPTALTKPG ADRFLISEAV RGEGAHLVDN EGRRFAFDYH PAGELAPRDV
310 320 330 340 350 360
VSRAIFSHLQ RTAVDPATAH VWLDMRPIPE DKIRLRFPNI VKVCQRWGID VFREPIPVAP
370 380 390 400 410 420
AAHYWMGGIA TNLKNQTNIP GLYAVGETAS TGVHGANRLA SNSLLECIVF GAQLANLTPA
430 440 450 460 470 480
DLIQHTETPA LPTREFKIDA SEWQHQQSQL AILREKLPRL VWQSAGICRE QSTLSVAIAT
490 500 510 520 530 540
VKSWQQDFAA LPLSQFLLSL QPNEPVSCNF SDTDQQLRLW AETGNLLDVA YLILKSAAFR
550 560 570
IESRGGHFRL DYPHSNPDWQ VHSLVQKHQW WQSPIMKS