Q8YCD5
Gene name |
rlmE |
Protein name |
Ribosomal RNA large subunit methyltransferase E |
Names |
23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase |
Species |
Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) |
KEGG Pathway |
bme:BMEII0597 |
EC number |
2.1.1.166: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8YCD5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8YCD5-F1 | Predicted | AlphaFoldDB |
No variants for Q8YCD5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8YCD5 | |||||
No associated diseases with Q8YCD5
6 regional properties for Q8YCD5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, Sec23/Sec24-type | 58 - 98 | IPR006895 |
| domain | Sec23/Sec24, trunk domain | 127 - 392 | IPR006896 |
| domain | Sec23/Sec24, helical domain | 520 - 618 | IPR006900 |
| domain | Gelsolin-like domain | 634 - 720 | IPR007123 |
| domain | Sec23/Sec24 beta-sandwich | 403 - 506 | IPR012990 |
| domain | Sec23, C-terminal | 612 - 732 | IPR037550 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.166 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| rRNA (uridine-2'-O-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKAGGNKGG | SRTGGRGGAG | SSNLHVRVKK | KAGTIKESSR | RWLERHLNDP | YVHKSRQDGY |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RSRAAYKLIE | INDRYNLLKK | GQKIIDLGAA | PGGWSQIAAR | IVGSTDENPQ | VVGIDYLHVD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PLPGVILLEM | DFLDDEAPQK | LMDALGDKPD | LVISDMAAPT | TGHRRTDHLR | TVHLCEVAAD |
| 190 | 200 | 210 | 220 | 230 | |
| FAVSVLKPGG | HFLTKTFQGG | TENELLALLK | QKFRSVHHVK | PPASRAESVE | LYLLARDFKG |