Q8Y4R7

PR
Gene name
pgi
Protein name
Glucose-6-phosphate isomerase
Names
GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI
Species
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
KEGG Pathway
lmo:lmo2367
EC number
5.3.1.9: Interconverting aldoses and ketoses
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

405-450 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8Y4R7

Entry ID Method Resolution Chain Position Source
AF-Q8Y4R7-F1 Predicted AlphaFoldDB

No variants for Q8Y4R7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8Y4R7

No associated diseases with Q8Y4R7

2 regional properties for Q8Y4R7

Type Name Position InterPro Accession
domain Cytochrome b/b6, N-terminal 75 - 287 IPR005797
domain Cytochrome b/b6, C-terminal 291 - 428 IPR005798

Functions

Description
EC Number 5.3.1.9 Interconverting aldoses and ketoses
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
carbohydrate derivative binding Binding to a carbohydrate derivative.
glucose-6-phosphate isomerase activity Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.
monosaccharide binding Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones HnC(=O)

3 GO annotations of biological process

Name Definition
gluconeogenesis The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
glucose 6-phosphate metabolic process The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTHIKFDYSK ALRFFEEREL DYLEPAVKAA HDSLHNGTGA GNDALGWINL PTDYDKEEFA
70 80 90 100 110 120
RIKKATEKIH SDSDVLIVIG IGGSYLGARA AIETLNHSFY NVLEKGARKT PQVFFAGNSI
130 140 150 160 170 180
SSSYLHDLIE VVGDRDFSVN VISKSGTTTE PAIAFRVFKE LLIKKYGEEG AKKRIYATTD
190 200 210 220 230 240
KAKGALKTLS DNEGYETFVV PDDVGGRFSV LTAVGLLPIA VSGVDIDALM NGAAAASKDF
250 260 270 280 290 300
DKPELKNNIA YQYAAARNVL YRKGKVTELL ISYEPGLQYF NEWWKQLFGE SEGKDKKGIY
310 320 330 340 350 360
PSSANFSTDL HSIGQYIQDG RRNLFETVIK VDKPRHNLTI NKEDVDLDGL NYLAGETVDF
370 380 390 400 410 420
VNTKAFEGTL LAHTDGEVPN FVVEVPELDA YTFGYLVYFF EKAVAISGYL NGVNPFDQPG
430 440
VEAYKANMFA LLGKPGFEDK KAELEKRLND