Q8Y457

PR
Gene name
truA
Protein name
tRNA pseudouridine synthase A
Names
tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I
Species
Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
KEGG Pathway
lmo:lmo2598
EC number
5.4.99.12: Transferring other groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

187-248 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8Y457

Entry ID Method Resolution Chain Position Source
AF-Q8Y457-F1 Predicted AlphaFoldDB

No variants for Q8Y457

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8Y457

No associated diseases with Q8Y457

2 regional properties for Q8Y457

Type Name Position InterPro Accession
domain Pseudouridine synthase I, TruA, alpha/beta domain 6 - 104 IPR020097-1
domain Pseudouridine synthase I, TruA, alpha/beta domain 144 - 248 IPR020097-2

Functions

Description
EC Number 5.4.99.12 Transferring other groups
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
pseudouridine synthase activity Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
RNA binding Binding to an RNA molecule or a portion thereof.
tRNA pseudouridine synthase activity Catalysis of the reaction: tRNA uridine = tRNA pseudouridine. Conversion of uridine in a tRNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.

1 GO annotations of biological process

Name Definition
tRNA pseudouridine synthesis The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTRYKAIISY DGSGFYGYQV QPNTRTVQAE IEKALTKMHK GKTVRVTASG RTDTGVHAKG
70 80 90 100 110 120
QVIHFDSELD ITAEKFQKAL QVMTPFDISF LTVEEVPDDF HARFGTVGKE YRYVVKRTKI
130 140 150 160 170 180
FDPFSRNFAL HYPYELDISK MKLASKRLIG EHDFTSFCSA RTERDSKVRT LYSIDFYEED
190 200 210 220 230 240
DETLVIAFQG NGFLYNMVRI LTGTLLDAGQ GRISPDDISE ALLARDRQKL ISKTAPPQGL
YLWRVDYE