Q8XZR0

PR
Gene name
clpB (RSc1335, RS02857)
Protein name
Chaperone protein ClpB
Names
Species
Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum)
KEGG Pathway
rso:RSc1335
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

111-185 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8XZR0

Entry ID Method Resolution Chain Position Source
AF-Q8XZR0-F1 Predicted AlphaFoldDB

No variants for Q8XZR0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8XZR0

No associated diseases with Q8XZR0

10 regional properties for Q8XZR0

Type Name Position InterPro Accession
domain UVR domain 603 - 638 IPR001943
domain AAA+ ATPase domain 332 - 476 IPR003593-1
domain AAA+ ATPase domain 718 - 895 IPR003593-2
domain ATPase, AAA-type, core 337 - 467 IPR003959-1
domain ATPase, AAA-type, core 717 - 888 IPR003959-2
domain Clp, repeat (R) domain 3 - 289 IPR004176
conserved_site ClpA/B, conserved site 1 427 - 439 IPR018368
domain Clp ATPase, C-terminal 894 - 983 IPR019489
conserved_site ClpA/B, conserved site 2 752 - 770 IPR028299
domain ClpA/ClpB, AAA lid domain 475 - 575 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLDKLTTRF QEALADAQSL ALGNDNPYIE PLHLLLAMLR QPDGATKNLL ARAGVNAKGL
70 80 90 100 110 120
EIALDNAIKR LPQVQGGEQV QVGRDLGSLL QATEKEGIKR GDQFIASELF LLAVADDKGE
130 140 150 160 170 180
AGRVAREHGL ARRALEAAID AVRGGQTVGS AEAESQREAL KKYTIDLTEQ ARIGKLDPVI
190 200 210 220 230 240
GRDDEIRRAI QILQRRTKNN PVLIGEPGVG KTAIVEGLAQ RIINGEVPES LKNKRVLVLD
250 260 270 280 290 300
MAGLLAGAKY RGEFEERLKA VLNDIAKEEG QTILFIDEIH TMVGAGKAEG AIDAGNMLKP
310 320 330 340 350 360
ALARGELHCI GATTLDEYRK YIEKDAALER RFQKVLVDEP SVEATIAILR GLQEKYELHH
370 380 390 400 410 420
GVEITDPAIV AAAELSHRYI TDRFLPDKAI DLIDEAAARI KMEIDSKPEA MDKLDRRLIQ
430 440 450 460 470 480
LKIEREAVKK ETDEASQKRL ELIEQEIERL QKEYADLEEI WKAEKGAAQG AAAVKEEIDR
490 500 510 520 530 540
VKLEIARLQR EGKLDKVAEL QYGRLPELEG KLKAATAAEA SGQRPPNKLL RTQVGAEEIA
550 560 570 580 590 600
EVVSRATGIP VSKMMQGERD KLLRMEDRLH ERVVGQDEAV RLVSDAIRRS RAGIADENKP
610 620 630 640 650 660
YGSFLFLGPT GVGKTELCKA LAGFLFDSEE HLIRIDMSEF MEKHSVSRLI GAPPGYVGYE
670 680 690 700 710 720
EGGYLTEAVR RKPYSVVLLD EVEKAHPDVF NILLQVLDDG RLTDGQGRTV DFKNTVIVMT
730 740 750 760 770 780
SNLGSQLIQQ MASESPDVIK GAVWQEVKTH FRPEFLNRID EVVVFHALDQ GHIESIARIQ
790 800 810 820 830 840
LQRLAARLAH MDLTLEISDP AVAKLASAGY DPVFGARPLK RAIQQQIENP VARMILEGRF
850 860
TPKDVVPVDY HDGHFTFDRV VR