Q8XDE7
Gene name |
kdsA |
Protein name |
2-dehydro-3-deoxyphosphooctonate aldolase |
Names |
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase |
Species |
Escherichia coli O157:H7 |
KEGG Pathway |
ecs:ECs_1720 |
EC number |
2.5.1.55: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8XDE7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8XDE7-F1 | Predicted | AlphaFoldDB |
No variants for Q8XDE7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8XDE7 | |||||
No associated diseases with Q8XDE7
No regional properties for Q8XDE7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8XDE7 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.55 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3-deoxy-8-phosphooctulonate synthase activity | Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| keto-3-deoxy-D-manno-octulosonic acid biosynthetic process | The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKQKVVSIGD | INVANDLPFV | LFGGMNVLES | RDLAMRICEH | YVTVTQKLGI | PYVFKASFDK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ANRSSIHSYR | GPGLEEGMKI | FQELKQTFGV | KIITDVHEPS | QAQPVADVVD | VIQLPAFLAR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QTDLVEAMAK | TGAVINVKKP | QFVSPGQMGN | IVDKFKEGGN | EKVILCDRGA | NFGYDNLVVD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| MLGFSIMKKV | SGNSPVIFDV | THALQCRDPF | GAASGGRRAQ | VAELARAGMA | VGLAGLFIEA |
| 250 | 260 | 270 | 280 | ||
| HPDPEHAKCD | GPSALPLAKL | EPFLRQMKAI | DDLVKGFEEL | DTSK |