Q8WZK5

PR
Gene name
SPBC839.02
Protein name
Putative arrestin-related trafficking adapter SPBC839.02
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC839.02
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

427-525 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8WZK5

Entry ID Method Resolution Chain Position Source
AF-Q8WZK5-F1 Predicted AlphaFoldDB

No variants for Q8WZK5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8WZK5

No associated diseases with Q8WZK5

2 regional properties for Q8WZK5

Type Name Position InterPro Accession
domain Arrestin-like, N-terminal 100 - 232 IPR011021
domain Arrestin C-terminal-like domain 263 - 422 IPR011022

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
calcium ion binding Binding to a calcium ion (Ca2+).
protein-macromolecule adaptor activity The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.
ubiquitin protein ligase binding Binding to a ubiquitin protein ligase enzyme, any of the E3 proteins.

3 GO annotations of biological process

Name Definition
clathrin-dependent endocytosis An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
ubiquitin-dependent endocytosis Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MYIPNLRNYH DKVFPYGPSS NGYNPVIRLT DRTTQPDPSQ HIYQEEKISK CEGLSYRARE
70 80 90 100 110 120
WLLLSSNSNA RVAIALAEPV LYLPGATSSE IQSEHSAVLR GSLCIQIYKP VKLKKIQLSF
130 140 150 160 170 180
KGKSRTEWPE GIPPKLFDTY EENSIMNHCW VFFHSEQKVD ENSHGAVWYK VLPHYADTAH
190 200 210 220 230 240
YPRSMECFYP GEYVYNFELP ISCTYPESIQ TDMGRVYYFL ETLVDRSSTF SGKSTGRIPI
250 260 270 280 290 300
ELIRSPCSTS VATSEPILVS KSWEDRLHYE VQVGEKCVVM GQVVPVNFKF TLLGEVKFHK
310 320 330 340 350 360
LRLFLMERRY YYCRQRSVRR KEKTRQLLLY ERSAPKNQCL LSDWKQVRPD VYELSDQVRI
370 380 390 400 410 420
PGCHDMAANI VHFDTTYPNI KITHTVRTVL RFSCENSPEL MGSAKYLEIY IDSPVRLLSC
430 440 450 460 470 480
RCSDGSTMLP AYCPIIPSSE VNFCSIDNRI IAGMNRDLAL DSDIIGNSPP SFDSWTAVPY
490 500
QAPPPKYDDI FQSGSSHDEN HDDN