Q8WNV5

PR
Gene name
SOX30 (QtsA-10245, QtsA-14427)
Protein name
Transcription factor SOX-30
Names
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
mcf:101925990
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

270-361 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8WNV5

Entry ID Method Resolution Chain Position Source
AF-Q8WNV5-F1 Predicted AlphaFoldDB

No variants for Q8WNV5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8WNV5

No associated diseases with Q8WNV5

1 regional properties for Q8WNV5

Type Name Position InterPro Accession
domain High mobility group box domain 336 - 406 IPR009071

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
  • Enriched at the chromocenter
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
chromocenter A region in which centric, heterochromatic portions from more than one chromosomes form a compact structure.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription activator activity, RNA polymerase II-specific A DNA-binding transcription factor activity that activates or increases transcription of specific gene sets transcribed by RNA polymerase II.
DNA-binding transcription repressor activity, RNA polymerase II-specific A DNA-binding transcription factor activity that represses or decreases the transcription of specific gene sets transcribed by RNA polymerase II.

5 GO annotations of biological process

Name Definition
negative regulation of transcription by RNA polymerase II Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
negative regulation of Wnt signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
positive regulation of transcription by RNA polymerase II Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
proacrosomal vesicle fusion Fusion of the membrane of proacrosomal vesicle with the membrane of another proacrosomal vesicle to form the acrosome.
spermatid development The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MERARPEPQP QQRPLRPAPP LLPVEGTTFW AAAVEPPPSP PTLSAAASAT LASSCGEAVA
70 80 90 100 110 120
SGLPPAVRRL LQVKPEQVLL LPQPQARDEE AAASPAQARL LQFRPDLRLL PPPSASEGAP
130 140 150 160 170 180
SRPELHPVQP RALHFKAKKQ ELGPGLDPSV GPRGGVETGP RASRVVKLEG PGPALAYFRG
190 200 210 220 230 240
NEKGKLEAEE VMRDAMKGGD GKSPAAIREG VIKTEEPERL LEDCRLDAEP ASNGLVHGSA
250 260 270 280 290 300
EVILAPTSGA FGPHQQDLRI PLTLHTVPPG ARIQFQGAPP SELIRLTKVP LTPVPIKMQS
310 320 330 340 350 360
LLEPSVKIET KDVPLTVLPS DAGIPDTPFS KDRNGHVKRP MNAFMVWARI HRPALAKANP
370 380 390 400 410 420
AANNAEISVQ LGLEWNKLSE EQKKPYYDEA QKIKEKHREE FPGWVYQPRP GKRKRFPLSV
430 440 450 460 470 480
SNVFSGTTQN IISTNPTTVY PYRSPTYSVV IPSLQNPITH PVGETSPAIQ LPTPAVQRPS
490 500 510 520 530 540
PVTLFQPSVS SAAQVAVQDP SLPLYPALPP QRFAGPSQTD THQLHSEGTH TVKQPTPVSL
550 560 570 580 590 600
ESTNRISNSA STAHARFATS TIQPPKEYSS VSPCPRSAPI PQASPIPHPH VYQPPPLGHP
610 620 630 640 650 660
ATLFGTPPRF SFHHPYFLPG PHYFPSSTCP YSRPPFGYGN FPSSMPECLG YYEDRYQKHE
670 680 690 700 710 720
AIFSALNRDY SFRDYSSERT HSENSRSCEN MNGTSFYNSH SHSGEEYLNP VPQLDIGALE
730 740 750
NVFTAPTSTP SSIQQVNVTD SDEEEEEKVL RDL