Q8VYU4
PR
Gene name |
CCR4-6 (At5g11350, F2I11_240) |
Protein name |
Carbon catabolite repressor protein 4 homolog 6 |
Names |
CCR4 homolog 6 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G11350 |
EC number |
3.1.13.4: Exoribonucleases producing 5'-phosphomonoesters |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8VYU4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8VYU4-F1 | Predicted | AlphaFoldDB |
71 variants for Q8VYU4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH10698404 | 24 | A>V | No | 1000Genomes | |
| tmp_5_3621673_A_G | 31 | T>A | No | 1000Genomes | |
| tmp_5_3621796_G_A | 43 | R>Q | No | 1000Genomes | |
| tmp_5_3621799_G_C | 44 | G>A | No | 1000Genomes | |
| ENSVATH10698415 | 47 | G>R | No | 1000Genomes | |
| ENSVATH06953251 | 49 | S>N | No | 1000Genomes | |
| tmp_5_3621864_A_T | 66 | T>S | No | 1000Genomes | |
| ENSVATH06953252 | 69 | S>Y | No | 1000Genomes | |
| tmp_5_3621893_T_G | 75 | H>Q | No | 1000Genomes | |
| tmp_5_3621913_G_A | 82 | R>Q | No | 1000Genomes | |
| tmp_5_3621921_G_A | 85 | E>K | No | 1000Genomes | |
| ENSVATH03046739 | 90 | H>Q | No | 1000Genomes | |
| ENSVATH06953253 | 92 | P>H | No | 1000Genomes | |
| ENSVATH10698416 | 94 | L>F | No | 1000Genomes | |
| ENSVATH03046740 | 101 | P>S | No | 1000Genomes | |
| tmp_5_3622046_G_C | 126 | Q>H | No | 1000Genomes | |
| ENSVATH06953254 | 152 | Q>H | No | 1000Genomes | |
| tmp_5_3622201_C_G | 178 | P>R | No | 1000Genomes | |
| tmp_5_3622204_G_A | 179 | G>D | No | 1000Genomes | |
| ENSVATH06953258 | 184 | V>A | No | 1000Genomes | |
| ENSVATH03046742 | 190 | I>V | No | 1000Genomes | |
| tmp_5_3622355_A_G | 207 | I>V | No | 1000Genomes | |
| tmp_5_3622401_T_C | 222 | V>A | No | 1000Genomes | |
| ENSVATH10698424 | 234 | C>G | No | 1000Genomes | |
| tmp_5_3622613_C_G | 243 | D>E | No | 1000Genomes | |
| tmp_5_3622616_A_T | 244 | L>F | No | 1000Genomes | |
| ENSVATH06953261 | 245 | E>K | No | 1000Genomes | |
| ENSVATH03046743 | 246 | E>K | No | 1000Genomes | |
| tmp_5_3623093_C_A | 309 | H>N | No | 1000Genomes | |
| ENSVATH10698456 | 312 | E>G | No | 1000Genomes | |
| ENSVATH00617185 | 323 | G>C | No | 1000Genomes | |
| tmp_5_3623759_C_T | 380 | P>S | No | 1000Genomes | |
| ENSVATH06953271 | 387 | D>H | No | 1000Genomes | |
| ENSVATH13994597 | 399 | K>E | No | 1000Genomes | |
| ENSVATH06953273 | 410 | P>S | No | 1000Genomes | |
| tmp_5_3623960_C_T | 418 | T>M | No | 1000Genomes | |
| ENSVATH10698462 | 422 | S>F | No | 1000Genomes | |
| ENSVATH03046748 | 424 | N>K | No | 1000Genomes | |
| ENSVATH06953276 | 429 | G>S | No | 1000Genomes | |
| ENSVATH06953277 | 434 | P>T | No | 1000Genomes | |
| tmp_5_3624167_G_A | 440 | A>T | No | 1000Genomes | |
| tmp_5_3624172_T_A | 441 | H>Q | No | 1000Genomes | |
| ENSVATH06953279 | 452 | T>M | No | 1000Genomes | |
| tmp_5_3624206_G_A | 453 | A>T | No | 1000Genomes | |
| tmp_5_3624219_A_T | 457 | K>M | No | 1000Genomes | |
| tmp_5_3624261_A_G | 471 | H>R | No | 1000Genomes | |
| ENSVATH10698463 | 485 | N>K | No | 1000Genomes | |
| tmp_5_3624318_G_T | 490 | C>F | No | 1000Genomes | |
| tmp_5_3624324_T_C | 492 | F>S | No | 1000Genomes | |
| ENSVATH06953281 | 506 | S>L | No | 1000Genomes | |
| tmp_5_3624381_T_A | 511 | L>H | No | 1000Genomes | |
| ENSVATH06953282 | 516 | I>M | No | 1000Genomes | |
| tmp_5_3624485_C_A | 546 | Q>K | No | 1000Genomes | |
| ENSVATH08409174 | 547 | T>I | No | 1000Genomes | |
| tmp_5_3624492_C_T | 548 | P>L | No | 1000Genomes | |
| ENSVATH06953283 | 568 | T>S | No | 1000Genomes | |
| tmp_5_3624567_T_C | 573 | M>T | No | 1000Genomes | |
| ENSVATH06953284 | 579 | K>I | No | 1000Genomes | |
| ENSVATH13994599 | 587 | A>P | No | 1000Genomes | |
| tmp_5_3624624_G_A | 592 | S>N | No | 1000Genomes | |
| tmp_5_3624626_T_G | 593 | L>V | No | 1000Genomes | |
| tmp_5_3624644_A_T | 599 | T>S | No | 1000Genomes | |
| tmp_5_3624726_G_A | 626 | S>N | No | 1000Genomes | |
| ENSVATH00617191 | 632 | S>G | No | 1000Genomes | |
| tmp_5_3624747_A_C | 633 | D>A | No | 1000Genomes | |
| tmp_5_3624762_G_A | 638 | S>N | No | 1000Genomes | |
| tmp_5_3624795_C_G | 649 | T>S | No | 1000Genomes | |
| ENSVATH00617192 | 711 | R>C | No | 1000Genomes | |
| ENSVATH00617193 | 749 | K>E | No | 1000Genomes | |
| tmp_5_3625402_C_A | 752 | P>H | No | 1000Genomes | |
| tmp_5_3625411_G_T | 755 | S>L | No | 1000Genomes |
No associated diseases with Q8VYU4
1 regional properties for Q8VYU4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Endonuclease/exonuclease/phosphatase | 221 - 485 | IPR005135 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.13.4 | Exoribonucleases producing 5'-phosphomonoesters |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3'-5'-exoribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. |
| metal ion binding | Binding to a metal ion. |
| poly(A)-specific ribonuclease activity | Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRRSRFVAQV | FSDVTFADAS | TISAPIFTMS | TRAPYRGARG | RGRGRGGRSF | SDRPYNDDAG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RDQFVTGDSH | FQSVHDANFR | FRHGEPYRQH | QPPLDQRQQP | PFNQNYEFRP | PPPSRGQWQQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FRQPNQFPSN | QNYAACPPPP | FYQNQMSRPP | PQQSFRQRPR | SKPSDYREWE | YAKTPPSPGS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EKFVVLSYNI | LADYLANDHW | RSLYFHIPRN | MLSWGWRKSK | LVFELSLWSA | DIMCLQEVDK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FQDLEEEMKH | RGYSAIWKMR | TGNAVDGCAI | FWRSNRFKLV | HEESIQFNQL | GLRDNVAQIC |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VLETLLTSHT | KENETPPPES | SAGSHRVVIC | NIHVLFNPKR | GDFKLGQVRT | LLDKAHAVSK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LWDDAPIVLC | GDFNCTPKSP | LYNFISDRKL | DLSGLARDKV | SGQVSAEFRP | PRPENYTTRY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| QSANKSPQGQ | VQPPNLITNA | HMENNSNIDV | GTAPSEKTSE | LPCGDTILAG | HEATSSSDQV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LPCENMASDC | QFGIENRKPD | DSGNLSTAED | LSSLTISDTE | PQHASSARED | LNTDRSVSSG |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LSETEQTPEE | ICSSDQDISS | SLSTKVDTFV | AEMKLDGLKL | DEPVVFAQDE | ESLGEDGETF |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LAKLHDNNEN | LSQKGELVSE | VPLKWSSEAL | NSDKITYSPS | SWTPMEIATA | TGDPERTTVE |
| 670 | 680 | 690 | 700 | 710 | 720 |
| HALELKSTYS | EVEGQANTRD | ENGEPVVTSY | HRCFMGTVDY | IWRSEGLQTV | RVLAPIPKQA |
| 730 | 740 | 750 | |||
| MQWTPGFPTP | KWGSDHIALV | SELAFCSSKT | LPKS |