Q8VYF7
Gene name |
WHY2 (At1g71260, F3I17.9) |
Protein name |
Single-stranded DNA-binding protein WHY2, mitochondrial |
Names |
Protein WHIRLY 2, AtWHY2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G71260 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q8VYF7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 4KOP | X-ray | 175 A | A/B/C/D | 45-212 | PDB |
| AF-Q8VYF7-F1 | Predicted | AlphaFoldDB |
18 variants for Q8VYF7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_26863381_T_A | 4 | Q>L | No | 1000Genomes | |
| tmp_1_26863269_C_T | 12 | S>N | No | 1000Genomes | |
| ENSVATH05125208 | 21 | F>L | No | 1000Genomes | |
| ENSVATH00137169 | 28 | G>D | No | 1000Genomes | |
| tmp_1_26863194_G_A | 37 | T>I | No | 1000Genomes | |
| ENSVATH00137168 | 43 | P>S | No | 1000Genomes | |
| tmp_1_26863016_C_T | 72 | V>I | No | 1000Genomes | |
| tmp_1_26862887_G_A | 84 | L>F | No | 1000Genomes | |
| tmp_1_26862860_T_G | 93 | M>L | No | 1000Genomes | |
| tmp_1_26862658_T_C | 131 | S>G | No | 1000Genomes | |
| ENSVATH14467884 | 163 | Y>* | No | 1000Genomes | |
| ENSVATH13790710 | 177 | N>I | No | 1000Genomes | |
| ENSVATH00137157 | 212 | H>Q | No | 1000Genomes | |
| tmp_1_26861918_T_A | 216 | E>D | No | 1000Genomes | |
| ENSVATH05125190 | 216 | E>V | No | 1000Genomes | |
| ENSVATH05125189 | 219 | P>S | No | 1000Genomes | |
| tmp_1_26861907_G_A | 220 | S>L | No | 1000Genomes | |
| tmp_1_26861904_C_T | 221 | R>K | No | 1000Genomes |
No associated diseases with Q8VYF7
No regional properties for Q8VYF7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8VYF7 | |||
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| DNA repair complex | A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| mRNA binding | Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns. |
| single-stranded DNA binding | Binding to single-stranded DNA. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response | Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. |
| DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMKQARSLLS | RSLCDQSKSL | FEASTLRGFA | SWSNSSTPGR | GFPGKDAAKP | SGRLFAPYSI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FKGKAALSVE | PVLPSFTEID | SGNLRIDRRG | SLMMTFMPAI | GERKYDWEKK | QKFALSPTEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GSLISMGSKD | SSEFFHDPSM | KSSNAGQVRK | SLSVKPHADG | SGYFISLSVN | NSILKTNDYF |
| 190 | 200 | 210 | 220 | 230 | |
| VVPVTKAEFA | VMKTAFSFAL | PHIMGWNRLT | GHVNTEALPS | RNVSHLKTEP | QLELEWDK |