Q8VWF8

PR
Gene name
RPOT2 (RPOT-B)
Protein name
DNA-directed RNA polymerase 2, chloroplastic/mitochondrial
Names
NsRpoT-B, T7 bacteriophage-type single subunit RNA polymerase 2
Species
Nicotiana sylvestris (Wood tobacco) (South American tobacco)
KEGG Pathway
EC number
2.7.7.6: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

114-218 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8VWF8

Entry ID Method Resolution Chain Position Source
AF-Q8VWF8-F1 Predicted AlphaFoldDB

No variants for Q8VWF8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8VWF8

No associated diseases with Q8VWF8

1 regional properties for Q8VWF8

Type Name Position InterPro Accession
domain Ribosomal protein L5 eukaryotic, C-terminal 239 - 302 IPR025607

Functions

Description
EC Number 2.7.7.6 Nucleotidyltransferases
Subcellular Localization
  • Plastid, chloroplast
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
DNA-directed RNA polymerase complex A protein complex that possesses DNA-directed RNA polymerase activity.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
plastid Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSTKTPISL TIKLNQFTDK PTGLDINPYH NSPIMWRNII KQLSSRTPQK LLFSSKNRTY
70 80 90 100 110 120
SFLGFGQDSI FKDNTKFRSL IPISCSNIVM GFQNLGEYLP GDEFLSRPLI KNQVNNNFCC
130 140 150 160 170 180
RKSYASVAEA VAVSSTDAEE DVSVVDEVHE LLTELKKEEK KQFAFRRRKQ RMLTSGMGHR
190 200 210 220 230 240
KYQTLKRRQV KVETEAWEQA AKEYKELLFD MCEQKLAPNL PYVKSLFLGW FEPLRDKIAE
250 260 270 280 290 300
EQELCSQGKS KAAYAKYFYQ LPADMMAVIT MHKLMGLLMT GGDHGTARVV QAALVIGDAI
310 320 330 340 350 360
EQEVRIHNFL EKTKKQKAEK DKQKEDGEHV TQEQEKLRKK VTNLMKKQKL RAVGQIVRRQ
370 380 390 400 410 420
DDSKPWGQDA RAKVGSRLID LLLQTAYIQP PANQLAVDPP DIRPAFVHSV RTVAKETKSA
430 440 450 460 470 480
SRRYGIIQCD ELVFKGLERT ARHMVIPYMP MLVPPVKWTG YDKGGHLYLP SYVMRTHGAR
490 500 510 520 530 540
QQREAVKRAS RNQLQPVFEA LDTLGNTKWR INKRVLSVVD RIWAGGGRLA DLVDRDDAPL
550 560 570 580 590 600
PEEPDTEDEA LRTKWRWKVK SVKKENRERH SQRCDIELKL AVARKMKDEE SFFYPHNVDF
610 620 630 640 650 660
RGRAYPMHPH LNHLGSDICR GVLEFAEGRP LGESGLRWLK IHLANLFAGG VEKLSLEGRI
670 680 690 700 710 720
GFTENHMDDI FDSSDKPLEG RRWWLNAEDP FQCLAVCINL SEAVRSSSPE TSVSHIPVHQ
730 740 750 760 770 780
DGSCNGLQHY AALGRDKLGA AAVNLVAGEK PADVYSGIAA RVLDIMKRDA QRDPAEFPDA
790 800 810 820 830 840
VRARVLVNQV DRKLVKQTVM TSVYGVTYIG ARDQIKRRLK ERGAIADDSE LFGAACYAAK
850 860 870 880 890 900
VTLTALGEMF EAARSIMTWL GECAKIIASE NEPVRWTTPL GLPVVQPYRK IGRHLIKTSL
910 920 930 940 950 960
QILTLQRETE KVMVKRQRTA FPPNFIHSLD GSHMMMTAVA CRRAGLNFAG VHDSYWTHAC
970 980 990 1000 1010
DVDKLNRILR EKFVELYEAP ILEKLLESFQ TSYPTLLFPP LPERGDFDMR DVLESPYFFN