Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8VIL2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8VIL2-F1 | Predicted | AlphaFoldDB |
No variants for Q8VIL2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8VIL2 | |||||
No associated diseases with Q8VIL2
1 regional properties for Q8VIL2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | RWD domain | 3 - 114 | IPR006575 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of NF-kappaB transcription factor activity | Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB. |
| positive regulation of hypoxia-inducible factor-1alpha signaling pathway | Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway. |
| positive regulation of protein sumoylation | Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEEVRQELS | ALAAIFCGPN | EWEMLSCSET | DGAVFRIHTT | AEGLVGEDVP | LELAFHLPVG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YPLCLPGISV | TSEHLTRAQC | VTAKEKLLGE | ARKLVSEPMV | HELVLWIQQN | LRLVLSQPET |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VSSHEKCTLP | ESATGDDGPW | MTLLRLDHMR | ARTKYVKAVE | KWASELRLTG | RLMFMGKLIL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ILLQGDRSNI | KEYLILQKTS | KVDVDSSGKK | CKEKMISVLS | ETKVQTEHKR | FLAFEVKEYS |
| 250 | 260 | ||||
| TLEELQKEFG | AAGLGELFSE | CVLGLVK |