Q8VED8
Gene name |
Mtfr2 (Dufd1, Fam54a) |
Protein name |
Mitochondrial fission regulator 2 |
Names |
DUF729 domain-containing protein 1 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:71804 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8VED8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8VED8-F1 | Predicted | AlphaFoldDB |
26 variants for Q8VED8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs229895216 | 15 | P>A | No | EVA | |
| rs3389101438 | 32 | F>Y | No | EVA | |
| rs3389090545 | 57 | I>N | No | EVA | |
| rs13463058 | 67 | C>F | No | EVA | |
| rs3400999236 | 71 | H>Q | No | EVA | |
| rs3400948578 | 72 | F>I | No | EVA | |
| rs3400948550 | 72 | F>Y | No | EVA | |
| rs3389100580 | 85 | D>E | No | EVA | |
| rs214194882 | 88 | L>I | No | EVA | |
| rs3389100575 | 98 | C>Y | No | EVA | |
| rs50810954 | 102 | D>E | No | EVA | |
| rs243523515 | 118 | K>E | No | EVA | |
| rs3389070225 | 133 | W>R | No | EVA | |
| rs3389059750 | 147 | T>S | No | EVA | |
| rs3389065967 | 180 | M>I | No | EVA | |
| rs265211943 | 188 | E>G | No | EVA | |
| rs48866598 | 200 | P>L | No | EVA | |
| rs232636120 | 204 | A>V | No | EVA | |
| rs253236963 | 209 | S>T | No | EVA | |
| rs229371698 | 215 | A>T | No | EVA | |
| rs213090345 | 228 | P>L | No | EVA | |
| rs46755612 | 240 | L>F | No | EVA | |
| rs3389090498 | 296 | V>I | No | EVA | |
| rs50444975 | 297 | R>K | No | EVA | |
| rs3389089659 | 309 | P>S | No | EVA | |
| rs3389100538 | 312 | K>N | No | EVA |
No associated diseases with Q8VED8
No regional properties for Q8VED8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8VED8 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| aerobic respiration | The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor. |
| mitochondrial fission | The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. |
| mitochondrion organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPRDGTNEQR | FLELPSPMSF | ILNILRNVLE | YFGVPVDQDL | LICQNKNCGS | ARSIVRIIGR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RLPLKPCRRP | HFELIPHVNS | TESDDYELRV | PSFADVLCVA | NDEEASCLRF | RHSLWQKKEE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RKIAPFYPSK | LTWDPSSPGL | RQNKTETDDL | PVNEAAIKKI | AALEDELTFL | RSQIAAIVAM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QDLRESRETG | FIDLSDEQVP | PSSATTGLSV | EPDHAPSVVL | PPPPPPPPPP | QFSLQPPSSL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PMQPGSANTH | DIDSLATEME | RQLSGVKKTD | DSHHSKSQRL | RDVPNMLDVL | KDVNKVRLRP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VERSPGGRPV | QKRKRRSSEW | DPVSLISNAL | KQKFAFQDDS | FDRENSSWEC | SPFSSPETSR |
| F |