Q8VDM6
Gene name |
Hnrnpul1 (Hnrpul1) |
Protein name |
Heterogeneous nuclear ribonucleoprotein U-like protein 1 |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:232989 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8VDM6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8VDM6-F1 | Predicted | AlphaFoldDB |
50 variants for Q8VDM6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388894329 | 114 | P>S | No | EVA | |
| rs3388892595 | 145 | E>K | No | EVA | |
| rs3388886078 | 162 | L>P | No | EVA | |
| rs3388888582 | 190 | D>G | No | EVA | |
| rs3388886103 | 216 | T>I | No | EVA | |
| rs3388892615 | 230 | S>N | No | EVA | |
| rs3388890903 | 250 | S>N | No | EVA | |
| rs3388877400 | 284 | R>G | No | EVA | |
| rs3397704982 | 298 | E>K | No | EVA | |
| rs3397685410 | 300 | P>A | No | EVA | |
| rs3397685393 | 301 | F>L | No | EVA | |
| rs3397677614 | 303 | Y>* | No | EVA | |
| rs3397439035 | 305 | Y>* | No | EVA | |
| rs3388889881 | 329 | V>A | No | EVA | |
| rs3388886041 | 332 | C>Y | No | EVA | |
| rs3388873520 | 361 | K>R | No | EVA | |
| rs3388883151 | 380 | V>A | No | EVA | |
| rs3388877455 | 382 | F>I | No | EVA | |
| rs3388883046 | 401 | I>V | No | EVA | |
| rs3388888524 | 408 | E>V | No | EVA | |
| rs3388889918 | 421 | E>D | No | EVA | |
| rs3388877410 | 432 | A>G | No | EVA | |
| rs3388864584 | 525 | F>L | No | EVA | |
| rs3388886034 | 536 | D>V | No | EVA | |
| rs3388881340 | 559 | V>F | No | EVA | |
| rs3388886235 | 590 | K>E | No | EVA | |
| rs3388870440 | 606 | P>L | No | EVA | |
| rs3388894355 | 608 | K>R | No | EVA | |
| rs232727561 | 612 | S>N | No | EVA | |
| rs3388892172 | 645 | R>P | No | EVA | |
| rs3388886031 | 647 | G>C | No | EVA | |
| rs220240422 | 651 | S>G | No | EVA | |
| rs3397677657 | 667 | G>C | No | EVA | |
| rs3397677677 | 670 | Y>H | No | EVA | |
| rs237236220 | 690 | N>S | No | EVA | |
| rs3388849750 | 724 | R>Q | No | EVA | |
| rs3388870486 | 731 | S>C | No | EVA | |
| rs3388888517 | 743 | A>S | No | EVA | |
| rs3388892214 | 746 | S>C | No | EVA | |
| rs13461779 | 754 | T>S | No | EVA | |
| rs3388892169 | 756 | P>L | No | EVA | |
| rs3388894304 | 770 | Y>N | No | EVA | |
| rs3388886056 | 782 | P>T | No | EVA | |
| rs3397284319 | 800 | Y>H | No | EVA | |
| rs3397750866 | 815 | S>I | No | EVA | |
| rs3397615442 | 816 | Y>* | No | EVA | |
| rs3396912120 | 821 | Q>L | No | EVA | |
| rs3388888518 | 837 | P>A | No | EVA | |
| rs3388864550 | 839 | Y>* | No | EVA | |
| rs3388883177 | 858 | T>A | No | EVA |
No associated diseases with Q8VDM6
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| ribonucleoprotein complex | A macromolecular complex that contains both RNA and protein molecules. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| enzyme binding | Binding to an enzyme, a protein with catalytic activity. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| response to virus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus. |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDVRRLKVNE | LREELQRRGL | DTRGLKAELA | ERLLAALEAE | EPEDERELEA | DDDPGLPGHN |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NEEVETEGGS | ELEGTAQPPP | PGLQPHPEPG | GYSGPDGHYV | MDNITRQNQF | YETPVIKQEN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESSYDRRPLD | MEPQQQVYHP | ELKTEMKQEA | PPSFLPPEAS | QLKTDRPQFQ | NRKRPFEENR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GRGYFEHRED | RRGRSPQPPA | EEDEDDFDDT | LVAIDTYNCD | LHFKVARDRS | SGYPLTIEGF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AYLWSGARAS | YGVRRGRVCF | EMKINEEISV | KHLPSTEPDP | HVVRIGWSLD | SCSTQLGEEP |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FSYGYGGTGK | KSTNSRFENY | GDKFAENDVI | GCFADFECGN | DVELSFTKNG | KWMGIAFRIQ |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KEALGGQALY | PHVLVKNCAV | EFNFGQRAEP | YCSVLPGFTF | IQHLPLSERI | RGTIGPKSKA |
| 430 | 440 | 450 | 460 | 470 | 480 |
| ECEILMMVGL | PAAGKTTWAI | KHAASNPSKK | YNILGTNAIM | DKMRVMGLRR | QRNYAGRWDV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LIQQATQCLN | RLIQIAARKK | RNYILDQTNV | YGSAQRRKMR | PFEGFQRKAI | VICPTDEDLK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DRTVKRTDEE | GKDVPDHAVL | EMKANFTLPD | VGDFLDEVLF | IELQREEADK | LVRQYNEEGR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| KAGPPPEKRF | DSRGGGFRGR | GGGGGFQRYD | NRGPPGGNRG | GFQNRGGGGG | SGGGGGNYRG |
| 670 | 680 | 690 | 700 | 710 | 720 |
| GFNRSGGGGY | NQNRWGNNNR | DNNNSNNRGN | YNRAPQQQPP | PQQPPPPQPP | PQQPPPPPSY |
| 730 | 740 | 750 | 760 | 770 | 780 |
| SPARNPPGAS | SYNKNSNIPG | SSANTSTPTV | SSYTPPQPSY | SQPPYNQGGY | TQGYTAPPPP |
| 790 | 800 | 810 | 820 | 830 | 840 |
| PPPPPAYNYG | SYGPYNPAPY | TPPPPPTAQT | YPQPSYNQYQ | QYAQQWSQYY | QNQSQWPPYY |
| 850 | |||||
| GNYDYGGYSG | STQGGTSTQ |