Q8VA42

PR
Gene name
S2
Protein name
RNA-directed RNA polymerase VP2
Names
Species
Aquareovirus A (isolate Chum salmon/Japan/CSRV/1981) (AQRV-A)
KEGG Pathway
vg:3773156
EC number
2.7.7.48: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

481-555 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q8VA42

Entry ID Method Resolution Chain Position Source

No variants for Q8VA42

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8VA42

No associated diseases with Q8VA42

1 regional properties for Q8VA42

Type Name Position InterPro Accession
domain RNA-directed RNA polymerase, reovirus 516 - 764 IPR007097

Functions

Description
EC Number 2.7.7.48 Nucleotidyltransferases
Subcellular Localization
  • Virion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
viral nucleocapsid The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.

4 GO annotations of molecular function

Name Definition
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.

1 GO annotations of biological process

Name Definition
viral genome replication Any process involved directly in viral genome replication, including viral nucleotide metabolism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPGTYAPVPN VYHLLDHLTF RSSVVIPNSN FVGRIWSDYW ALQDNIVIRV SPEGAKDADY
70 80 90 100 110 120
CHNSNISPIL SPLKTITEYG TLHPTIDKDA SERGYPSARM ASSFFKLASC QARQVKIDPT
130 140 150 160 170 180
RFLEFLLVTA SSPRVPSGVD SDQPNPWLPE TSPALQAIWQ IMQRYKLNGN YYAPALVVNT
190 200 210 220 230 240
GAVWWIPPPG RTNCVTVQFL ITDLINLAVN AFATRLAPEL EMCAVRVYLA AASTPNYAHA
250 260 270 280 290 300
LLDLKSIFPN LSLHSMYREG EFGGKCPRIE WTEPRSSYRF KWIGVTQLYE GLRPLTPSRD
310 320 330 340 350 360
SKALLKMRDS GLEDVAKVII TMRRDHPRHT SDSVRFVRGV LSLISGMYLV RPPTMSVLRE
370 380 390 400 410 420
YSQTPQIEEP IPPDWWTGAV GNLSYFNDKA KGPLAHLYSV WLEAARQVVM DPSTHDPLTQ
430 440 450 460 470 480
AIYKTQFVTP RGGSSAALKQ ALVESKVELP DFSGTGVKRS SKIYQTAQLA HFSFQTLIPT
490 500 510 520 530 540
IMGQVTLGIR NQVQRRARSI MPMSNPQQTV SVPHTLVANY INKHMNRSTT SGSAVQDKVI
550 560 570 580 590 600
PLLLYASTPP RTVINVDIKA CDASITYAAF LAPICGAMHQ GFDLGDPSLP FMNVPSSTQY
610 620 630 640 650 660
DRRNPAAPYN RPVSGLQTMT QHLARLYQAG FSYKVDDPFS SGNSFVFPTT TFPSGSTATS
670 680 690 700 710 720
TEHTANNGAM ADFFLREYVP QHAKSSTLKF IVKDMNIQNN YVCQGDDGML IIPDLGTKRI
730 740 750 760 770 780
SPEDLAELME LLEKYGRGFG WVYDIDSSDS AEYLKLYALF GARIPNISRH PPVGKEYASP
790 800 810 820 830 840
ETGEIWPSLV NIAMGSFYNG VTDCLEWRDW LKFSWAFACF ASRGSFHPKT GPRVDAQYPV
850 860 870 880 890 900
WSFIYMGLPP ILLPGQTPFL TSVYMPAGDQ GIFAILHQWR DYLTARATSD YPPLKRRHPV
910 920 930 940 950 960
WHLADVPSLL SDLGVYRGYW AAQVSRRPEP SPDDADPASV EAMSAALSTY LLKDPVLRDR
970 980 990 1000 1010 1020
VVRGTNAWRR LTDTHPGRLP SRVPSLLDVP TRWIKAGRDA DKPRPSAVAM MMKDIQRAAS
1030 1040 1050 1060 1070 1080
SSRKDFSRLL ELYLHVHVHL GPPVPLAVDP EVPHVAGADI LNDDHWYKVT SLGPIAQSTK
1090 1100 1110 1120 1130 1140
KYFDATLFVG KTVSGLDVEA VDATLLRMSI LGAEPEEYHA FLAGIGMSDA EAHRIASAIS
1150 1160 1170 1180 1190 1200
LADAQIVQLA RTVNLAVPSS WMSLDFDTLI RSHSYPRQPG ISDSSTLVRE RASWINSVLR
1210 1220 1230
LLCATVAMSR VGPVCQATVS SVDGGVNQIV GCLRAWMRDV