Q8UII5

PR
Gene name
gshB
Protein name
Glutathione synthetase
Names
GSH synthetase, GSH-S, GSHase, Glutathione synthase
Species
Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
KEGG Pathway
atu:Atu0310
EC number
6.3.2.3: Acid--amino-acid ligases (peptide synthases)
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

199-279 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8UII5

Entry ID Method Resolution Chain Position Source
AF-Q8UII5-F1 Predicted AlphaFoldDB

No variants for Q8UII5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8UII5

No associated diseases with Q8UII5

3 regional properties for Q8UII5

Type Name Position InterPro Accession
domain Prokaryotic glutathione synthetase, N-terminal 6 - 122 IPR004215
domain Prokaryotic glutathione synthetase, ATP-binding 126 - 296 IPR004218
domain ATP-grasp fold 127 - 311 IPR011761

Functions

Description
EC Number 6.3.2.3 Acid--amino-acid ligases (peptide synthases)
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
glutathione synthase activity Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate.
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKIKNVAIQ MDHVSGINIA GDSTFAISLE AQARGYRLFH YTPERLSMRD GKIYATVEQM
70 80 90 100 110 120
ELRDIKGDHF SLSEPERVDL STMDVIHLRQ DPPFDMAYIT STHLLERIHP KTLVVNDPAW
130 140 150 160 170 180
VRNSPEKIFV TEFADLMPKT LITKDVSEIA RFRNEMGDII LKPLYGNGGA GVFHSARDDR
190 200 210 220 230 240
NFSSLLEMFG QMFREPYIAQ EYLPDVRKGD KRILLVDGEP VGAINRVPAE NDARSNMHAG
250 260 270 280 290 300
GRPEPTELTA REQEICRRIG PALRERGFLF VGIDVIGDYM TEINVTSPTG IREVRKFGGA
310
DVASLLWDAI EKKRDAQDF