Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8UGK1

Entry ID Method Resolution Chain Position Source
AF-Q8UGK1-F1 Predicted AlphaFoldDB

No variants for Q8UGK1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8UGK1

No associated diseases with Q8UGK1

7 regional properties for Q8UGK1

Type Name Position InterPro Accession
repeat WD40 repeat 405 - 453 IPR001680-1
repeat WD40 repeat 587 - 622 IPR001680-2
repeat WD40 repeat 625 - 664 IPR001680-3
repeat WD40 repeat 668 - 708 IPR001680-4
repeat WD40 repeat 720 - 763 IPR001680-5
domain BOP1, N-terminal domain 146 - 405 IPR012953
conserved_site WD40 repeat, conserved site 431 - 445 IPR019775

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Cell inner membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
small ribosomal subunit rRNA binding Binding to small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.

1 GO annotations of biological process

Name Definition
ribosomal small subunit biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMDIMTDHEN PAVTGEDNAL PTRSGFVALI GPTNAGKSTL VNRLVGAKVS IVSHKVQTTR
70 80 90 100 110 120
AVMRGIAIHK NAQIVFMDTP GIFKPRRRLD RAMVTSAWGG AKDADLILLL IDSERGLKGD
130 140 150 160 170 180
AEAILEGLKD VPQKKILCLN KIDQVKREDL LKLAAAANEK VAFDRTFMIS ATNGSGCEDL
190 200 210 220 230 240
MDYLVETLPE GPWYYPEDQI SDLPMRQLAA EITREKLFLR LHQELPYASH VETEKWEERK
250 260 270 280 290 300
DGSVRIEQVI YVERDSQKKI ALGKNGDAIK AISTASRKEL SEILEQPVHL FLFVKVRENW
310
GDDPERFREM GLEFPRG