Q8U705

PR
Gene name
argH2
Protein name
Argininosuccinate lyase 2
Names
ASAL 2, Arginosuccinase
Species
Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
KEGG Pathway
atu:Atu4651
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

447-504 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8U705

Entry ID Method Resolution Chain Position Source
AF-Q8U705-F1 Predicted AlphaFoldDB

No variants for Q8U705

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8U705

No associated diseases with Q8U705

2 regional properties for Q8U705

Type Name Position InterPro Accession
domain Fumarate lyase, N-terminal 60 - 307 IPR022761
domain Argininosuccinate lyase, C-terminal 373 - 448 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADINPRQSD TSKFPDPVYK ETVLRPLFDG AKNHHVDGFR RIDRAHLVML RETGILDAET
70 80 90 100 110 120
AAKIAGALED IDRTIEPSEL VYTGEVEDFF FLIEKELKAR IGVDVAGRLH TARSRNDIDH
130 140 150 160 170 180
TLFKIGLKDK IDTLTAKARV LLKALIDAAE RNQSTLIVAY THGQPAQPTT FGHYLSAAIE
190 200 210 220 230 240
VLIRDIERFT EARHIVDLSP MGAAAITTSG FPIDRARVAE LLGFAAPLRN SYSCIAAVDY
250 260 270 280 290 300
TTATYGAIEL MFLHLGRLIQ DFQFWTSFEV GQIYVPNSLV QISSIMPQKR NPVPIEHLRH
310 320 330 340 350 360
LASQTFGRAR TMLDVMHNTP FTDMNDSEGE TQSMGYEAFA SAGRVLDLLA SLVGQISIDP
370 380 390 400 410 420
ERVDQNIRRS CITITELADS LVRIEDLSFR QAHEIAATVA KSVVALKGDL PNDGYQPFLG
430 440 450 460 470 480
AFSGLTGRET GIDEEKFRQI VSPEHFVAVR SRFGGPAPEP MREAFAAYRG KLGAFEAEAQ
490 500
RSTNHEAAKA AELAEKFTAL TGAR