Q8U4H6
Gene name |
PF0112 |
Protein name |
Polyribonucleotide 5'-hydroxyl-kinase PF0112 |
Names |
Polynucleotide kinase PF0112 |
Species |
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
KEGG Pathway |
pfu:PF0112 |
EC number |
2.7.1.78: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8U4H6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8U4H6-F1 | Predicted | AlphaFoldDB |
No variants for Q8U4H6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8U4H6 | |||||
No associated diseases with Q8U4H6
1 regional properties for Q8U4H6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain | 36 - 210 | IPR032319 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.78 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| polydeoxyribonucleotide 5'-hydroxyl-kinase activity | Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEVNKASLTY | DVPEDREYAT | KRILSLKRPS | KIMVIGDVDT | GKTTLIVYLA | NELISRGFKV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AIVDADVGQK | GILPPATISL | ALADMKFSSL | SELKPLIHYF | VGSITPSQFF | GEMIVGTMRL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SEIGKKFADY | VLIDTTGMIY | GSGVELKRLK | IEAVKPDLIL | ALEKKEELNP | IVSGFEDKTI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KLKVSENARS | YSRSERRQIR | QEKWRKYFEN | AKIVSFSLEN | VVVTGTSLFQ | GSDIREEEKS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LLERLFKWVI | LHGRRIGDKY | FVVKADVAEV | PRVVDKNVVR | YFDFEKLSNL | LVGLLNEEGL |
| 310 | 320 | 330 | 340 | 350 | |
| CLGVGIIKGI | NFGEKRIDIL | TPVSEIENVR | EIRFGRIRVR | EDGEELGILD | REAL |