Q8U4A8
Gene name |
atpC |
Protein name |
V-type ATP synthase subunit C |
Names |
V-ATPase subunit C |
Species |
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) |
KEGG Pathway |
pfu:PF0180 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8U4A8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8U4A8-F1 | Predicted | AlphaFoldDB |
No variants for Q8U4A8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8U4A8 | |||||
No associated diseases with Q8U4A8
No regional properties for Q8U4A8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8U4A8 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| proton-transporting V-type ATPase, V0 domain | A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| proton-transporting ATP synthase activity, rotational mechanism | Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out). |
| proton-transporting ATPase activity, rotational mechanism | Enables the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| proton motive force-driven plasma membrane ATP synthesis | The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEISTITMIL | DTTLVAVFAW | VAYKTGSLIW | KYTPYSYPNA | RIRAMEARLL | SDQRLLELAE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SKELENFVVN | LEDSDYGKRL | SELKSYSVEE | IEKALDLSFV | DTILLFQKIM | PKRVRGFFEV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MLEEWDVRNI | VNVVKAKITG | LPAQDFVIPV | GKILNKVKAM | VEAKTMEEIL | VILEGTEYEE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PVRKLILKEI | NLPEFEHLMY | SLHYQKLLNY | VNSRKGEEKV | ILSEFVSSLI | DSKNISLILR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AKASGINAEK | LKIMLIPGGS | ISRNVLEAMI | SAEDPLMALT | ELEKTKYAEV | VKNSREAVEK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GDISTVEKQL | RRYIQQRMKE | QSQFYPLSVA | VALSYMLQKE | NEIRKLKAIV | RLIADRVRPE |
| RIKEIVGEVT |