Q8U3H8

PR
Gene name
rps6e
Protein name
30S ribosomal protein S6e
Names
Small ribosomal subunit protein eS6
Species
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
KEGG Pathway
pfu:PF0488
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

54-125 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

5 structures for Q8U3H8

Entry ID Method Resolution Chain Position Source
4V4N EM 900 A G 1-125 PDB
4V6U EM 660 A AG 1-125 PDB
5JB3 EM 534 A G 1-125 PDB
5JBH EM 534 A G 1-125 PDB
AF-Q8U3H8-F1 Predicted AlphaFoldDB

No variants for Q8U3H8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8U3H8

No associated diseases with Q8U3H8

3 regional properties for Q8U3H8

Type Name Position InterPro Accession
domain Ribosomal protein S5, C-terminal 104 - 173 IPR005324
domain Ribosomal protein S5, N-terminal 26 - 90 IPR013810
conserved_site Ribosomal protein S5, N-terminal, conserved site 43 - 75 IPR018192

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

1 GO annotations of molecular function

Name Definition
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MATFKLVISD PKSGIAKQVE ITGAETEKLI GKRIGDQIPA KELNINLNEL FGKEFPEDVK
70 80 90 100 110 120
LEIRGGTDKD GFPMRPDIHG PRRVRVLLSK GPGFRPKEKG ERRKKTVRGN TISPEIVQVN
VKLVY