Q8U3E3

PR
Gene name
ftsZ2
Protein name
Cell division protein FtsZ 2
Names
Species
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
KEGG Pathway
pfu:PF0525
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-52 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8U3E3

Entry ID Method Resolution Chain Position Source
AF-Q8U3E3-F1 Predicted AlphaFoldDB

No variants for Q8U3E3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8U3E3

No associated diseases with Q8U3E3

3 regional properties for Q8U3E3

Type Name Position InterPro Accession
domain Fumarase C, C-terminal 407 - 460 IPR018951
conserved_site Fumarate lyase, conserved site 316 - 325 IPR020557
domain Fumarate lyase, N-terminal 11 - 341 IPR022761

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Assembles at midcell at the inner surface of the cytoplasmic membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cell division site The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

3 GO annotations of biological process

Name Definition
division septum assembly The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a division septum are not able to exchange intracellular material.
FtsZ-dependent cytokinesis A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.
protein polymerization The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLEKLLEQAG IKLDFDGEEE KKSEIVDEFS GYKINIAVVG VGGSGNNTIS RLYDLGVQGA
70 80 90 100 110 120
DLIAMNTDAQ HLAITKAHKK VLLGKHITQG KGSGGDPKVG YLAAEASAQE IAAAVDGYDL
130 140 150 160 170 180
VFITAGMGNG TGTGAAPVVA RIVKETARNN GRFQEPLVVS VVTFPFKTEG TVRIEKAKWG
190 200 210 220 230 240
IQRLLEYSDT VIIIQNDKLL ELVPKLPLQS AFRFADELIA RMVKGIVETI KLNSIVNIDF
250 260 270 280 290 300
ADVYSIMKGG GPALIGIGES DSNNRAVDAV NNALTNKMLD VEFGSGEKAL VHFTIGPDVS
310 320 330 340 350 360
LEEINKAMEV VYEKLSEKSE IKWGAMVDPE MGKTVRAMVI MTGVRSPYIL GNVNALTDSS
370 380 390 400
SWVVPKDRRL IGDPRIEKMF PDFNGSRAGR KRPSVGDAIL KELGFKEL