Q8U1R5

PR
Gene name
eif2a
Protein name
Translation initiation factor 2 subunit alpha
Names
aIF2-alpha, eIF-2-alpha
Species
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
KEGG Pathway
pfu:PF1140
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

54-147 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8U1R5

Entry ID Method Resolution Chain Position Source
AF-Q8U1R5-F1 Predicted AlphaFoldDB

No variants for Q8U1R5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8U1R5

No associated diseases with Q8U1R5

3 regional properties for Q8U1R5

Type Name Position InterPro Accession
domain S1 domain 8 - 83 IPR003029
domain RNA-binding domain, S1 10 - 83 IPR022967
domain IF2a, S1-like domain 9 - 84 IPR044126

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
RNA binding Binding to an RNA molecule or a portion thereof.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPRRAREYPE EGELVVATVK RVHNYGAFLD LDEYPGKEGF MHISEVASTW VKNIRDYLRE
70 80 90 100 110 120
GQKVVAKVIR VDPKKGHIDL SLRRVTQQQR KAKLQEFKRA QKAENLLKLA AEKLGKDFEE
130 140 150 160 170 180
AWREVWVPLE NEWGEVYAAF EDAARNGIEV LKGYVPDEWL PVLKEIIDSY VEVPTVTIDA
190 200 210 220 230 240
EFEITVPKPN GIEIIKEALI KARDRANQEK DIEVKFTYLG APRYRIDITA PDYYKAEEVL
250 260 270
EDIAEEILRV IKEAGGEATL LRKEKRIRKV KKRKK