Q8U0M0

PR
Gene name
rrp42
Protein name
Exosome complex component Rrp42
Names
Species
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
KEGG Pathway
pfu:PF1567
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

46-142 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8U0M0

Entry ID Method Resolution Chain Position Source
AF-Q8U0M0-F1 Predicted AlphaFoldDB

No variants for Q8U0M0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8U0M0

No associated diseases with Q8U0M0

2 regional properties for Q8U0M0

Type Name Position InterPro Accession
domain Exoribonuclease, phosphorolytic domain 1 33 - 167 IPR001247
domain Exoribonuclease, phosphorolytic domain 2 192 - 256 IPR015847

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
exosome (RNase complex) A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSNDEIVAGI MRDYILNLLK EKKRIDDRGF EDYRPIEVEV GVIEKAEGSA LVKLGNTQVL
70 80 90 100 110 120
VGIKATLGEP FPDTPNMGVM TTNVELVPLA SPTFEPGPPD ERAIELARVI DRGIRESRAL
130 140 150 160 170 180
NLEKMVIAPG KIVRVVFIDV HVLDHDGNLM DAIGIGAIAA LLNARVPKVL YNEETGEVEI
190 200 210 220 230 240
LEEKEPLPVE KIPISVTFAK IGNYLVVDPT LEEEQIMDGR LTITTDETGH ISAVQKSEGG
250 260 270
AFKLEEVMYA VETAFKKAEE IRKIILNALE KANNSEE