Q8U016

PR
Gene name
rpl19e
Protein name
50S ribosomal protein L19e
Names
Large ribosomal subunit protein eL19, PfeL19
Species
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
KEGG Pathway
pfu:PF1806
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

25-117 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q8U016

Entry ID Method Resolution Chain Position Source
4V4N EM 900 A Q 1-150 PDB
4V6U EM 660 A BQ 1-150 PDB
AF-Q8U016-F1 Predicted AlphaFoldDB

No variants for Q8U016

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8U016

No associated diseases with Q8U016

3 regional properties for Q8U016

Type Name Position InterPro Accession
domain Ribosomal protein L19/L19e 3 - 149 IPR000196
conserved_site Ribosomal protein L19/L19e conserved site 7 - 26 IPR023638
domain Ribosomal protein L19e, archaeal 4 - 148 IPR033936

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosolic large ribosomal subunit The large subunit of a ribosome located in the cytosol.

2 GO annotations of molecular function

Name Definition
large ribosomal subunit rRNA binding Binding to large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.
structural constituent of ribosome The action of a molecule that contributes to the structural integrity of the ribosome.

1 GO annotations of biological process

Name Definition
translation The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNTLKMQRRI AAEILKCGEN RIWIDPERID DVASAITRED IKRLIKEGVI KKKPIKGQSR
70 80 90 100 110 120
YRAKIRHEQK KKGRHRGPGS RKGKKTARMG KKELWIKTIR ALRKELRKLK AQKKIDRKTY
130 140
RMLYIRAKGG QFKNKHQLYL FLEEHGLLKK