Q8TYV1
Gene name |
ppcA |
Protein name |
Phosphoenolpyruvate carboxylase |
Names |
PEPC, PEPCase |
Species |
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) |
KEGG Pathway |
mka:MK0190 |
EC number |
4.1.1.31: Carboxy-lyases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8TYV1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8TYV1-F1 | Predicted | AlphaFoldDB |
No variants for Q8TYV1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8TYV1 | |||||
No associated diseases with Q8TYV1
No regional properties for Q8TYV1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8TYV1 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 4.1.1.31 | Carboxy-lyases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| phosphoenolpyruvate carboxylase activity | Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| carbon fixation | A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates). |
| oxaloacetate metabolic process | The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle. |
| tricarboxylic acid cycle | A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEKVREARIA | RTLATQHPDA | TKFVRVQEEP | EEAVECLVEL | GAEEYMVDFE | GKLTPYLQPI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QVLMELYDAG | VRVGEERFVI | VRVPSATKEN | VLRQVQALLG | VMEANSELLK | EDPDARGIFE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VVHPMTSSPE | ELVETVDRIS | YARRFASREL | DVPLKAGNLR | IIPLIEEVPE | LLDIRNILTG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| YVEGMREIGM | DVSYLRVFIG | RSDPALSYGH | LPAVLACKLA | IFEVYELSDE | LGVPMAPILG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GGCLPFRGHI | RPGMEEEFVE | EYAGTATYTV | QSGFRYDHDR | EKAVASIRRI | NELAANDPLQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LSGDDIEYLV | LATAIFMKHY | LSVFFRCIGT | LNIVADMIPN | TRDRLARKGP | VGYARDIPEP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DRVGAQCKDL | GDVGRELYRE | LRRMRVEKLP | ELPRAIKFTG | ACYTVGMPPE | LIGTGRGLAE |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IEERLGEDAL | DAVISRLYPM | LREDLQFAVE | YTFLETAGSV | LPSSGVAMVN | TDLEYCVEYL |
| 490 | 500 | 510 | 520 | 530 | |
| DLEPPSDFEY | QNLVHTLEPY | LRYVVSEGGV | EEVNPFVRDL | LLEMGRMRGS | LG |