Q8TUS5

PR
Gene name
pstK (MK1679)
Protein name
L-seryl-tRNA(Sec) kinase
Names
O-phosphoseryl-tRNA(Sec) kinase, PSTK
Species
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
KEGG Pathway
mka:MK1679
EC number
2.7.1.164: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

138-255 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8TUS5

Entry ID Method Resolution Chain Position Source
AF-Q8TUS5-F1 Predicted AlphaFoldDB

No variants for Q8TUS5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8TUS5

No associated diseases with Q8TUS5

2 regional properties for Q8TUS5

Type Name Position InterPro Accession
domain Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain 154 - 309 IPR006131
domain Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding 4 - 144 IPR006132

Functions

Description
EC Number 2.7.1.164 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
L-seryl-tRNA(Sec) kinase activity Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
selenocysteinyl-tRNA(Sec) biosynthetic process The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRLLILTGPP GSGKTCFARE LARELRQEGW RVAHVEADAL RGFLWDEFDP KLEQVARELF
70 80 90 100 110 120
LKSVETCLDA ELDLVIADDT NYYSSMRREL ALLALERKVP WGIVYLRTGL DTCLRRNRER
130 140 150 160 170 180
GEPIPEEVVR RIYDRFEPPE PDRWWERATL VLDDSRVSEE VLEFVESGLR VEKPKKRRRR
190 200 210 220 230 240
TDPSSVNEVD VRTRQVMGEL MRRLSETGAA TQELGRKLSE LRREIVSSVE DPEKAVREFR
250
RRAEEVIREC LHGDG