Q8TIX0

PR
Gene name
MA_4020
Protein name
Putative ABC transporter ATP-binding protein MA_4020
Names
Species
Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)
KEGG Pathway
mac:MA_4020
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-71 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8TIX0

Entry ID Method Resolution Chain Position Source
AF-Q8TIX0-F1 Predicted AlphaFoldDB

No variants for Q8TIX0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8TIX0

No associated diseases with Q8TIX0

4 regional properties for Q8TIX0

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 46 - 281 IPR003439
domain AAA+ ATPase domain 72 - 295 IPR003593
domain ABC transporter, CbiO/EcfA subunit 47 - 258 IPR015856
conserved_site ABC transporter-like, conserved site 181 - 195 IPR017871

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
ATP-binding cassette (ABC) transporter complex A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATPase-coupled transmembrane transporter activity Primary active transporter of a solute across a membrane, via the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance across a membrane. The transport protein may be transiently phosphorylated (P-type transporters), or not (ABC-type transporters and other families of transporters). Primary active transport occurs up the solute's concentration gradient and is driven by a primary energy source.

1 GO annotations of biological process

Name Definition
cobalt ion transport The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTISTLSSSY GNAQDVPAED SDRHGSIEPG SEKAANAVER SGIPILEVKN LCHRYPHLDA
70 80 90 100 110 120
NTLEEINLKV YKGERVAVLG ANGAGKSTLF KHLNGILKPL SGEVLVKGEK ITKKNVRMCR
130 140 150 160 170 180
ETVGIVFQDP DDQVLAPSVE EDIAFGPINM GLSSEEVEKR VKEALKMVGL EGFEERAPHH
190 200 210 220 230 240
LSGGQKKLVA IAGILAMRPE VIVLDEPTAG LDPLSSARFL ELIMKMNKEL GITLLLSTHD
250 260 270 280 290 300
VDVVPYFAER VFVLHHGKLE ADGIPEEIFS DPELLRKAHL RLPRIAEIFE MLQQEGVDIN
310 320
IKITAEKARD EILRVMDSRF QTFRMG