Q8TGY9
Gene name |
pgk2 |
Protein name |
2-phosphoglycerate kinase |
Names |
2PGK |
Species |
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938) |
KEGG Pathway |
mka:MK0868 |
EC number |
2.7.2.16: Phosphotransferases with a carboxy group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8TGY9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8TGY9-F1 | Predicted | AlphaFoldDB |
No variants for Q8TGY9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8TGY9 | |||||
No associated diseases with Q8TGY9
4 regional properties for Q8TGY9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Phosphoglucose isomerase, conserved site | 260 - 273 | IPR018189-1 |
| conserved_site | Phosphoglucose isomerase, conserved site | 486 - 503 | IPR018189-2 |
| domain | Phosphoglucose isomerase, SIS domain 1 | 116 - 279 | IPR035476 |
| domain | Phosphoglucose isomerase, SIS domain 2 | 326 - 507 | IPR035482 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.2.16 | Phosphotransferases with a carboxy group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| kinase activity | Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. |
| phosphotransferase activity, carboxyl group as acceptor | Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor). |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSEKSSRKER | DEKTEKETAR | QGKHRRIRVK | SRHYEMPFSR | GVLARSLTAI | GVEPHKAYEI |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ALKIKEELQD | EGIEEISTDE | LADIIRTKLE | EIDETLAERY | ELWRRIKKRE | EPIIVLIGGA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGVGTSTIAS | EVGHRLGITN | VIGTDAIREV | MRRVLAEELY | PTLYESSYTA | WKRLRYEPAE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DPVITGFLDH | SEPVVVGIEG | VVNRSINEGI | HVIVEGVHIV | PRLIKKEILN | YPNVFVFMLA |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VEDEEAHKWR | FYARSRDTKL | SRPAERYLKY | FEEIRRIHDF | LVEDAEEHDI | PVINNEHIDE |
| 310 | 320 | ||||
| TVDQIVSYIS | SKLLKGEREL | SKSVSWW |