Q8TGG8

PR
Gene name
gda1 (AfA14E5.03c, AFUA_1G12150)
Protein name
Probable guanosine-diphosphatase
Names
GDPase
Species
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
KEGG Pathway
afm:AFUA_1G12150
EC number
3.6.1.42: In phosphorus-containing anhydrides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-78 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8TGG8

Entry ID Method Resolution Chain Position Source
AF-Q8TGG8-F1 Predicted AlphaFoldDB

No variants for Q8TGG8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8TGG8

No associated diseases with Q8TGG8

No regional properties for Q8TGG8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8TGG8

Functions

Description
EC Number 3.6.1.42 In phosphorus-containing anhydrides
Subcellular Localization
  • Golgi apparatus membrane ; Single-pass type II membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

3 GO annotations of molecular function

Name Definition
GDP phosphatase activity Catalysis of the reaction: GDP + H2O = GMP + phosphate.
nucleoside diphosphate phosphatase activity Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleoside monophosphate + phosphate.
UDP phosphatase activity Catalysis of the reaction: UDP + H2O = UMP + phosphate.

2 GO annotations of biological process

Name Definition
nucleoside diphosphate catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.
protein N-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAQTQRSRYL KTGAIVAALL LMLLWISPSR PMHPSFPQGQ PSTSAPAKGK CSKPHDPKKP
70 80 90 100 110 120
LIQYALMIDA GSQGSRIHVY RFNNCGPSPE LEDEVFFQTE PKKGGSGLSS YKEDAEGAAK
130 140 150 160 170 180
SLDPLMEVAM KNVPDEYKSC SPIAVKATAG LRMLGPELSQ KILDAVRNRL ETVYPFPVVS
190 200 210 220 230 240
KEKGGVEIMD GSDEGVYAWI TTNYLLGKIG GPDETPTAAV FDLGGGSTQI VFQPTFPKSK
250 260 270 280 290 300
SGGMPERLSE GDHKYDLQFG GRHFELYQHS HLGYGLMAAR KAIHTSIIEN MLASSPKDLS
310 320 330 340 350 360
WLKQPIPNPC IGPEMEKNVT LEFPEGHKLA PEVQVTMVGP KVGSTAAQCR GLAEKTLNKE
370 380 390 400 410 420
AACTLAPCSF NGVHQPSLEK TFAREDVYIF SYFYDRTKPL GMPDSFTLDE LHQLTSTVCG
430 440 450 460 470 480
GEDSWGIFAG IEGALKELRD RPEWCLDLNF MMSLLHTGYE MPLSREVKIA KKIKNRELGW
490 500
CLGASLPLLS QESGWTCRIK EVS