Q8TFF9

PR
Gene name
SPBPB8B6.03
Protein name
Putative amidase PB8B6.03
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBPB8B6.03
EC number
3.5.1.4: In linear amides
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-68 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8TFF9

Entry ID Method Resolution Chain Position Source
AF-Q8TFF9-F1 Predicted AlphaFoldDB

No variants for Q8TFF9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8TFF9

No associated diseases with Q8TFF9

2 regional properties for Q8TFF9

Type Name Position InterPro Accession
conserved_site Amidase, conserved site 207 - 238 IPR020556
domain Amidase signature domain 79 - 535 IPR023631

Functions

Description
EC Number 3.5.1.4 In linear amides
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
amidase activity Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
fatty acid amide hydrolase activity Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.
indoleacetamide hydrolase activity Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA.

1 GO annotations of biological process

Name Definition
fatty acid catabolic process The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDTPTWEVVA ALKRNQVLNS IPKEWRKPNI RKEMISSGYV NTYEYLNLIL PPEENAITNL
70 80 90 100 110 120
SMLELATNIA KGNYTSYNVT KAFCHRAALA HQILNCCIEI FFDEALKKAK ELDDVFQKTS
130 140 150 160 170 180
KVVGPFHGIP ISLKDQVDLP GKDSSIGYVS LVGKPKTEIA LLAKILQDKG AIFYVKTTVP
190 200 210 220 230 240
MAMMAPQTVS NLHGYTYNAL NINLSSGGSS GGEGALLGSG ASCCGIGTDI GGSIRIPSCF
250 260 270 280 290 300
QGLYALKPST GRISYLNVTN SYSGQELIPS VIGPMARSLK DIEFFTETVI ASEAWKIDSK
310 320 330 340 350 360
LLPIPWKNQS HLKSKKLIFG VLKTDGIVKP HPPIIRALNE VVAVLEKSGY EVIEISIPFQ
370 380 390 400 410 420
KDMLDTVVKV FSADARFEIN NESQKTGEPV VSVVKRFVSD KIFKKPITVN EWWDLGNQVY
430 440 450 460 470 480
KIRQMFLELW NNTAIQTLSG NSIDAIIAPI WASTSFLPES KADHLYTSLF NICDCPCVVF
490 500 510 520 530 540
PFTKVDANID LSDVSYKPLN EEDKENNDMY DPVLFDNMPV CLQVVTKKLE EEKCLAAASS
IMDCLTN