Q8SVI7
Gene name |
RIO1 (ECU05_1070) |
Protein name |
Probable serine/threonine-protein kinase RIO1 homolog |
Names |
|
Species |
Encephalitozoon cuniculi (strain GB-M1) (Microsporidian parasite) |
KEGG Pathway |
ecu:ECU05_1070 |
EC number |
2.7.11.1: Protein-serine/threonine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8SVI7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8SVI7-F1 | Predicted | AlphaFoldDB |
No variants for Q8SVI7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8SVI7 | |||||
No associated diseases with Q8SVI7
1 regional properties for Q8SVI7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | HemY, N-terminal | 27 - 116 | IPR010817 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.11.1 | Protein-serine/threonine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
5 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| hydrolase activity | Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. |
| metal ion binding | Binding to a metal ion. |
| protein serine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. |
| protein serine/threonine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
| ribosome biogenesis | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKETRAEKRK | KDKSDRATVD | KVLDKRTLKV | LERLQARGKL | VNLQGSLCTG | KESNVYLGEA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STSLCSKFIK | NRYSVTEEPG | REGQIVPVVV | KIFKTSIMSF | RDRERYIRSE | KRFQRFCTSN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SRKLIKVWAE | KEVRNLKRLN | NAGIPSPEPI | YLKNNILVMT | QIGRCSEVAP | RLRDASIKDL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EGCYQQCVKI | IRDMYKKAGL | VHADLSEFNL | LYFEGVVYVI | DVGQSVEIDH | DNAQRFLIMD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| INNINSFFSR | KGVSVAKGND | LFEEISGNVI | PLYLKDIDIG | RDAFIPSRVS | EVGNEEDLLA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FAADSRSREF | GSTTDSDLSS | TGEASVEDSD | ASLGATESRG | GGNIREEKKR | KKKTVKELNR |
| 370 | 380 | ||||
| IRRASRISKK | EKKRIFKRYI | GMKKRKN |