Q8SPV9
Gene name |
FCGRT (FCRN) |
Protein name |
IgG receptor FcRn large subunit p51 |
Names |
IgG Fc receptor II-a, Fc-gamma RII-a, Fc-gamma-RIIa, FcRII-a, FcRn, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor |
Species |
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) |
KEGG Pathway |
mcf:102128913 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8SPV9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8SPV9-F1 | Predicted | AlphaFoldDB |
No variants for Q8SPV9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8SPV9 | |||||
No associated diseases with Q8SPV9
4 regional properties for Q8SPV9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Immunoglobulin/major histocompatibility complex, conserved site | 273 - 279 | IPR003006 |
| domain | Immunoglobulin C1-set | 216 - 285 | IPR003597 |
| domain | Immunoglobulin-like domain | 202 - 289 | IPR007110 |
| domain | MHC class I-like antigen recognition-like | 28 - 197 | IPR011161 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| endosome membrane | The lipid bilayer surrounding an endosome. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| IgG binding | Binding to an immunoglobulin of an IgG isotype. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MRVPRPQPWA | LGLLLFLLPG | SLGAESHLSL | LYHLTAVSSP | APGTPAFWVS | GWLGPQQYLS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| YDSLRGQAEP | CGAWVWENQV | SWYWEKETTD | LRIKEKLFLE | AFKALGGKGP | YTLQGLLGCE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LSPDNTSVPT | AKFALNGEEF | MNFDLKQGTW | GGDWPEALAI | SQRWQQQDKA | ANKELTFLLF |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SCPHRLREHL | ERGRGNLEWK | EPPSMRLKAR | PGNPGFSVLT | CSAFSFYPPE | LQLRFLRNGM |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AAGTGQGDFG | PNSDGSFHAS | SSLTVKSGDE | HHYCCIVQHA | GLAQPLRVEL | ETPAKSSVLV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VGIVIGVLLL | TAAAVGGALL | WRRMRSGLPA | PWISLRGDDT | GSLLPTPGEA | QDADSKDINV |
| IPATA |