Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8SPE7

Entry ID Method Resolution Chain Position Source
AF-Q8SPE7-F1 Predicted AlphaFoldDB

No variants for Q8SPE7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8SPE7

No associated diseases with Q8SPE7

No regional properties for Q8SPE7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8SPE7

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
  • Nucleus
  • Using N-terminally tagged constructs, has been found in the nucleus
  • C-terminally tagged constructs are targeted exclusively to mitochondria
  • This discrepancy may be explained by masking of a potential N-terminal mitochondrial targeting signal by the tag
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
ribonucleoprotein complex A macromolecular complex that contains both RNA and protein molecules.
ribosome An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAASVRKARS LLGLTATLAP GSRGYRAPPP PRREPGPWWP DPEDLLTHRW QLGPRYAAKQ
70 80 90 100 110 120
FARYGAASGV APGSLWPSPE QLRELEAEER EWYPSLATMQ ESLRVKHLAE EQKRREREQH
130 140 150 160 170 180
IAECMAKMPQ MIVNWQQQQR ERWEKAQADK ERRARLQAEA QELLGYQVNP KSARFQELLQ
190 200 210 220
DLEKKERKRL KEEKQRQKQE ARAAALAAAA AQDPAASGAP SS