AiPD: Autoinhibited Protein Database

Gene name	MFDX2
Protein name	Adrenodoxin-like protein 2, mitochondrial
Names	Mitochondrial ferredoxin 2, AtMFDX2
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT4G21090
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

2-107 (Predicted disordered autoinhibitory region) PR

2-107 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8S904-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_4_11258231_A_C	13	I>M	No	1000Genomes
tmp_4_11258221_G_A	17	L>F	No	1000Genomes
tmp_4_11258098_G_A	24	S>L	No	1000Genomes
tmp_4_11258099_A_G	24	S>P	No	1000Genomes
ENSVATH00527625	25	M>I	No	1000Genomes
tmp_4_11258082_C_A	29	R>S	No	1000Genomes
tmp_4_11258078_G_T	31	L>I	No	1000Genomes
ENSVATH06740836	35	Y>D	No	1000Genomes
tmp_4_11258057_A_T	38	Y>N	No	1000Genomes
tmp_4_11257525_G_C	49	T>S	No	1000Genomes
ENSVATH06740809	51	S>R	No	1000Genomes
ENSVATH12100536	59	N>K	No	1000Genomes
ENSVATH06740808	61	H>Q	No	1000Genomes
tmp_4_11257453_T_A	73	K>I	No	1000Genomes
ENSVATH06740807	74	G>D	No	1000Genomes
ENSVATH06740806	77	K>E	No	1000Genomes
ENSVATH06740805	78	T>A	No	1000Genomes
ENSVATH06740797	84	T>I	No	1000Genomes
ENSVATH12100478	90	G>R	No	1000Genomes
ENSVATH02898282	92	E>K	No	1000Genomes
ENSVATH06740793	111	D>E	No	1000Genomes
tmp_4_11257228_T_C	112	I>V	No	1000Genomes
ENSVATH12100443	134	T>I	No	1000Genomes
ENSVATH06740781	135	K>E	No	1000Genomes
ENSVATH12100437	169	A>T	No	1000Genomes
tmp_4_11256721_G_T	179	A>D	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	2Fe-2S ferredoxin-type iron-sulfur binding domain	81 - 184	IPR001041
binding_site	Adrenodoxin, iron-sulphur binding site	118 - 128	IPR018298

		Description
EC Number
Subcellular Localization	Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

Name	Definition
2 iron, 2 sulfur cluster binding	Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
electron transfer activity	Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
metal ion binding	Binding to a metal ion.

Name	Definition
electron transport chain	A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors.
P450-containing electron transport chain	A electron transport chain in which one or more electron carriers operate to transfer electrons from donors to a cytochrome P450 protein or domain. Electron carriers operating in this chain include FAD-containing flavoproteins or domains, FMN domains, ferredoxins and cytochrome b5. The reduced cytochrome P450 functions as the terminal oxidase and participates in a wide range of biochemical pathways.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins