Q8S307

PR
Gene name
BZR1
Protein name
Protein BRASSINAZOLE-RESISTANT 1
Names
Protein BIN2 SUBSTRATE 2
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G75080
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-67 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q8S307

Entry ID Method Resolution Chain Position Source
5ZD4 X-ray 217 A A/B/C/D 21-104 PDB
8QT5 X-ray 269 A A/B/C/D/E/F/G 169-175 PDB
AF-Q8S307-F1 Predicted AlphaFoldDB

13 variants for Q8S307

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05147287 10 S>T No 1000Genomes
tmp_1_28185764_C_T 19 A>V No 1000Genomes
tmp_1_28185769_G_A 21 A>T No 1000Genomes
ENSVATH05147288 42 A>S No 1000Genomes
tmp_1_28186336_C_A 95 P>H No 1000Genomes
ENSVATH00143317 106 T>A No 1000Genomes
tmp_1_28186416_A_G 122 S>G No 1000Genomes
tmp_1_28186420_C_A 123 P>H No 1000Genomes
ENSVATH05147303 210 A>G No 1000Genomes
tmp_1_28186820_T_G 256 F>L No 1000Genomes
ENSVATH05147308 282 A>T No 1000Genomes
tmp_1_28186897_C_T 282 A>V No 1000Genomes
tmp_1_28186910_G_C 286 M>I No 1000Genomes

No associated diseases with Q8S307

4 regional properties for Q8S307

Type Name Position InterPro Accession
domain Helicase, C-terminal 394 - 553 IPR001650
domain Helicase/UvrB, N-terminal 166 - 332 IPR006935
domain Helicase superfamily 1/2, ATP-binding domain 162 - 361 IPR014001
domain Bacteriophage T5, Orf172 DNA-binding 5 - 77 IPR018306

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.

5 GO annotations of biological process

Name Definition
brassinosteroid mediated signaling pathway The series of molecular signals mediated by the detection of brassinosteroid.
negative regulation of DNA-templated transcription Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
plant ovule development The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
seed development The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTSDGATSTS AAAAAAAAAA ARRKPSWRER ENNRRRERRR RAVAAKIYTG LRAQGDYNLP
70 80 90 100 110 120
KHCDNNEVLK ALCVEAGWVV EEDGTTYRKG CKPLPGEIAG TSSRVTPYSS QNQSPLSSAF
130 140 150 160 170 180
QSPIPSYQVS PSSSSFPSPS RGEPNNNMSS TFFPFLRNGG IPSSLPSLRI SNSCPVTPPV
190 200 210 220 230 240
SSPTSKNPKP LPNWESIAKQ SMAIAKQSMA SFNYPFYAVS APASPTHRHQ FHTPATIPEC
250 260 270 280 290 300
DESDSSTVDS GHWISFQKFA QQQPFSASMV PTSPTFNLVK PAPQQMSPNT AAFQEIGQSS
310 320 330
EFKFENSQVK PWEGERIHDV GMEDLELTLG NGKARG