Q8RWZ3
Gene name |
IBR3 |
Protein name |
Probable acyl-CoA dehydrogenase IBR3 |
Names |
Protein INDOLE-3-BUTYRIC ACID RESPONSE 3 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G06810 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8RWZ3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8RWZ3-F1 | Predicted | AlphaFoldDB |
52 variants for Q8RWZ3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_3_2146550_G_A | 6 | G>D | No | 1000Genomes | |
| ENSVATH05787171 | 12 | I>V | No | 1000Genomes | |
| ENSVATH00310183 | 17 | R>L | No | 1000Genomes | |
| tmp_3_2146606_C_T | 25 | R>C | No | 1000Genomes | |
| ENSVATH05787172 | 30 | N>D | No | 1000Genomes | |
| ENSVATH10533941 | 40 | Q>L | No | 1000Genomes | |
| tmp_3_2146666_C_G | 45 | Q>E | No | 1000Genomes | |
| tmp_3_2146667_A_G | 45 | Q>R | No | 1000Genomes | |
| ENSVATH10533942 | 70 | L>V | No | 1000Genomes | |
| tmp_3_2146878_A_G | 86 | D>G | No | 1000Genomes | |
| ENSVATH13880659 | 99 | T>I | No | 1000Genomes | |
| ENSVATH05787186 | 114 | A>T | No | 1000Genomes | |
| ENSVATH00310186 | 115 | V>I | No | 1000Genomes | |
| tmp_3_2147188_G_A | 119 | A>T | No | 1000Genomes | |
| ENSVATH05787187 | 137 | P>A | No | 1000Genomes | |
| tmp_3_2147367_C_G | 141 | P>R | No | 1000Genomes | |
| tmp_3_2147378_A_T | 145 | N>Y | No | 1000Genomes | |
| ENSVATH05787191 | 146 | A>S | No | 1000Genomes | |
| tmp_3_2147621_A_C | 187 | K>N | No | 1000Genomes | |
| ENSVATH10533985 | 202 | P>S | No | 1000Genomes | |
| ENSVATH05787196 | 246 | V>I | No | 1000Genomes | |
| tmp_3_2147909_C_G | 257 | L>V | No | 1000Genomes | |
| ENSVATH05787198 | 269 | M>I | No | 1000Genomes | |
| ENSVATH13880662 | 275 | V>F | No | 1000Genomes | |
| tmp_3_2148152_C_A | 308 | A>E | No | 1000Genomes | |
| tmp_3_2148488_G_A | 355 | G>R | No | 1000Genomes | |
| tmp_3_2148513_A_T | 363 | E>V | No | 1000Genomes | |
| tmp_3_2148545_G_T | 374 | V>F | No | 1000Genomes | |
| ENSVATH00310192 | 389 | S>L | No | 1000Genomes | |
| ENSVATH05787206 | 392 | S>R | No | 1000Genomes | |
| ENSVATH13880663 | 393 | L>F | No | 1000Genomes | |
| ENSVATH05787207 | 406 | V>I | No | 1000Genomes | |
| ENSVATH00310194 | 464 | D>H | No | 1000Genomes | |
| tmp_3_2148988_A_C | 470 | R>S | No | 1000Genomes | |
| tmp_3_2149017_A_G | 480 | H>R | No | 1000Genomes | |
| ENSVATH02120105 | 490 | L>F | No | 1000Genomes | |
| tmp_3_2149055_G_A | 493 | E>K | No | 1000Genomes | |
| ENSVATH10533988 | 499 | E>D | No | 1000Genomes | |
| tmp_3_2149073_G_A | 499 | E>K | No | 1000Genomes | |
| ENSVATH05787211 | 506 | I>V | No | 1000Genomes | |
| ENSVATH05787212 | 507 | M>I | No | 1000Genomes | |
| ENSVATH10533990 | 530 | I>V | No | 1000Genomes | |
| ENSVATH13880685 | 573 | S>Y | No | 1000Genomes | |
| ENSVATH13880686 | 575 | R>G | No | 1000Genomes | |
| ENSVATH00310197 | 600 | V>F | No | 1000Genomes | |
| tmp_3_2149805_A_G | 629 | I>V | No | 1000Genomes | |
| ENSVATH05787222 | 630 | S>N | No | 1000Genomes | |
| tmp_3_2150126_G_T | 703 | A>S | No | 1000Genomes | |
| ENSVATH00310199 | 711 | K>N | No | 1000Genomes | |
| ENSVATH10534038 | 723 | L>F | No | 1000Genomes | |
| tmp_3_2150532_T_C | 785 | S>P | No | 1000Genomes | |
| tmp_3_2150542_T_G | 788 | V>G | No | 1000Genomes |
No associated diseases with Q8RWZ3
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| peroxisome | A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| acyl-CoA dehydrogenase activity | Catalysis of the reaction: acyl-CoA + oxidized |
| flavin adenine dinucleotide binding | Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| fatty acid beta-oxidation using acyl-CoA dehydrogenase | A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively). |
| root hair elongation | The process in which the root hair grows longer. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q6JQN1 | ACAD10 | Acyl-CoA dehydrogenase family member 10 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGSSTGDLVT | RIQSAHRFDH | DALFRFAADN | VSGFPTNPSQ | FKVSQFGHGQ | SNPTFLIEVG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| SGSSLKRYVL | RKKPPGKLLQ | SAHAVDREFQ | VLRALGEHTQ | VPVPKVFCLC | TDPAVIGTAF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YIMEFMEGRI | FIDPKLPNVA | PERRNAIYRA | TAKALASLHS | ADVDAIGLEK | YGRRGNYCKR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QIDRWFKQYL | ASTSEGKPER | NPKMFELVDW | LRKNIPAEDS | TGATSGLVHG | DFRIDNLVFH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PSEDRVIGII | DWELSTLGNQ | MCDVAYSCMH | YIVNVQLDKE | HVSEGFETTG | LPEGMLSMPE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FLLEYCSASG | KPWPAANWKF | YVAFSLFRAA | SIYTGVYSRW | LMGNASAGER | ARNTGVQANE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LVESALGYIA | RENVLPEHPP | SVQRDVSPSY | ESLVDGSGRF | IPNRKVLELR | QKLIKFMETH |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IYPMENEFSK | LAQSDMRWTV | HPQEEKLKEM | AKREGLWNLF | VPVDSAARAR | RELAATENKH |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NLSGKSFDQL | FGEGLTNLEY | GYLCEIMGRS | VWAPQVFNCG | APDTGNMEVI | LRYGNKEQIS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EWLIPLLEGR | IRSGFAMTEP | QVASSDATNI | ECSIRRQGDS | YVINGTKWWT | SGAMDPRCRV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LILMGKTDFN | APKHKQQSMI | LVDMRTPGIS | VKRPLTVFGF | DDAPHGHAEI | SFENVVVPAK |
| 670 | 680 | 690 | 700 | 710 | 720 |
| NILLGEGRGF | EIAQGRLGPG | RLHHCMRLIG | AAERGMELMA | QRALSRKTFG | KFIAQHGSFV |
| 730 | 740 | 750 | 760 | 770 | 780 |
| SDLAKLRVEL | EGTRLLVLEA | ADHLDKFGNK | KARGILAMAK | VAAPNMALKV | LDTAIQVHGA |
| 790 | 800 | 810 | 820 | ||
| AGVSSDTVLA | HLWATARTLR | IADGPDEVHL | GTIGKLELQR | ASKL |