Q8RDQ0
Gene name |
mraY |
Protein name |
Phospho-N-acetylmuramoyl-pentapeptide-transferase |
Names |
UDP-MurNAc-pentapeptide phosphotransferase |
Species |
Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355) |
KEGG Pathway |
fnu:FN1459 |
EC number |
2.7.8.13: Transferases for other substituted phosphate groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8RDQ0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8RDQ0-F1 | Predicted | AlphaFoldDB |
No variants for Q8RDQ0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8RDQ0 | |||||
No associated diseases with Q8RDQ0
2 regional properties for Q8RDQ0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site | 64 - 76 | IPR018480-1 |
| conserved_site | Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site | 187 - 198 | IPR018480-2 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.8.13 | Transferases for other substituted phosphate groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| phospho-N-acetylmuramoyl-pentapeptide-transferase activity | Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol. |
| phosphotransferase activity, for other substituted phosphate groups | Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor). |
| UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity | Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cell cycle | The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. |
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| cell wall macromolecule biosynthetic process | The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall. |
| cell wall organization | A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. |
| peptidoglycan biosynthetic process | The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls. |
| regulation of cell shape | Any process that modulates the surface configuration of a cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLYFLAEHLA | KLEFLKSIYL | RAFLGFVISF | CIVLFAGRPF | IKYLKIKKFG | EEIRDDGPSS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HFSKKGTPTM | GGVLIIAAVL | LTSIFINDLT | NSLILLVLLS | TIMFAAIGFI | DDYRKFTVSK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KGLAGKKKLL | FQGAIGLIIW | AYIYFIGLTG | RPMVDLSLIN | PISAYPYYIG | AIGLFFLIQI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VLMGTSNAVN | ITDGLDGLAI | MPMIICSTIL | GVIAYFTGHT | ELSSHLHLFY | TVGSGELSVF |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LSAVTGAGLG | FLWYNCYPAQ | IFMGDTGSLT | LGGILGVIAI | ILKQELMLPI | MGFIFVLEAL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SVILQVGSFK | LRGKRIFKMA | PIHHHFELMG | IPESKVTMRF | WIGTLIFGII | ALGAIKMRGI |
| L |