Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8R5S4

Entry ID Method Resolution Chain Position Source
AF-Q8R5S4-F1 Predicted AlphaFoldDB

No variants for Q8R5S4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8R5S4

No associated diseases with Q8R5S4

6 regional properties for Q8R5S4

Type Name Position InterPro Accession
domain Peptidase M41 500 - 688 IPR000642
domain AAA+ ATPase domain 283 - 422 IPR003593
domain ATPase, AAA-type, core 287 - 419 IPR003959
conserved_site ATPase, AAA-type, conserved site 390 - 408 IPR003960
domain Peptidase M41, FtsH extracellular 77 - 194 IPR011546
domain AAA ATPase, AAA+ lid domain 442 - 486 IPR041569

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Located at the septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIDKKQKPVK EEIVGIIFLA FTLISFLSLY TDSTGIIGKH IGIFLKGFFG TGSYVISALL
70 80 90 100 110 120
LVFALMFLFT NKNFIKLHRS MALLGLFLMF ISLNQLYYFP VLTDFKDYLS VAYISGINNT
130 140 150 160 170 180
GGGIIGSLIV YFLVKMVGII GSYILLISFT AIFIVLITDI SLVSLIKSSY DKLKDRKKVS
190 200 210 220 230 240
AKNKLQDKMA EKKAEEVEST EELVEVEKKE RIDVPIEIVE QVEEERKVYE KAFLEKEEGE
250 260 270 280 290 300
YTPPPITLLK EAIPSPKIKN EVLLEKAKKI EETLRNFGIE AKVVQVTKGP AITRFELQPS
310 320 330 340 350 360
AGVKVSRIVS LTDDLALSLA APSVRIEAPI PGKSAIGIEV PNEKITPVYL REVIDSKKFR
370 380 390 400 410 420
SFKSELAIGL GKDIAGNIVI ADLAKMPHLL IAGATGSGKS VCINSLIVSL LYKASPKQVK
430 440 450 460 470 480
MILIDPKVVE LNIYNGIPHL LTPVVTDPKK AAGVLNWAVQ EMIRRYSLFA DHGVRDIESY
490 500 510 520 530 540
NEKYKEERLY KIVIIIDELS DLMMVSPAEV EEYIFRLAQM ARAAGIHLVI ATQRPSVDVI
550 560 570 580 590 600
TGVIKANIPS RISFAVSSQI DSRTILDMTG AEKLLGKGDM LFDPIGASKP IRVQGAFISE
610 620 630 640 650 660
EEVEAVVNFL KENYSSHYEE IKVEEKTNGK NLDEEEDELL EDAVSVILET GQASISLLQR
670 680 690 700
KLRIGYARAA RIIDQLEQKG IISGYDGAKP RQIILPREEI QKILERKSV