Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8R1F6

Entry ID Method Resolution Chain Position Source
AF-Q8R1F6-F1 Predicted AlphaFoldDB

34 variants for Q8R1F6

Variant ID(s) Position Change Description Diseaes Association Provenance
rs3389180115 15 I>N No EVA
rs3389203953 54 E>D No EVA
rs3389232149 68 T>M No EVA
rs3389214996 93 V>A No EVA
rs3389190837 116 G>S No EVA
rs3402998765 124 G>R No EVA
rs3389190853 128 G>E No EVA
rs3389190817 138 A>S No EVA
rs3389180147 142 A>T No EVA
rs3389227327 146 L>I No EVA
rs3389220699 148 A>V No EVA
rs3389220713 327 N>Y No EVA
rs3389212341 350 S>F No EVA
rs3389203957 395 V>L No EVA
rs3389190901 408 D>N No EVA
rs3389203976 409 A>P No EVA
rs3402830769 440 N>S No EVA
rs3389215020 448 P>L No EVA
rs3389186628 495 L>I No EVA
rs3389217703 501 V>L No EVA
rs3389219461 504 N>D No EVA
rs3389216639 527 H>R No EVA
rs251466496 578 L>F No EVA
rs3389180198 606 A>V No EVA
rs3389212386 612 T>I No EVA
rs3389232201 634 E>K No EVA
rs27031651 637 T>S No EVA
rs3389230346 660 S>G No EVA
rs3389220732 710 K>* No EVA
rs3389209647 712 C>Y No EVA
rs3402420394 715 K>T No EVA
rs3389212364 716 G>C No EVA
rs3389216668 730 G>D No EVA
rs3389209656 738 V>M No EVA

No associated diseases with Q8R1F6

No regional properties for Q8R1F6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8R1F6

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Golgi apparatus membrane ; Lipid-anchor
  • Shuttles between the cytosol and the Golgi apparatus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

8 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoplasmic microtubule Any microtubule in the cytoplasm of a cell.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
extrinsic component of Golgi membrane The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi medial cisterna The middle Golgi cisterna (or cisternae).
Golgi trans cisterna The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8IV36 HID1 Protein HID1 Homo sapiens (Human) PR
10 20 30 40 50 60
MGSADSKLNF RKAVIQLTTK TQPVEATDNA FWDQFWADTA TSVQDVFALV PAAEIRAVRE
70 80 90 100 110 120
ESPSNLATLC YKAVEKLVQG AEGGCHSEKE KQVVLNCSRL LTRVLPYIFE DPDWRGFFWS
130 140 150 160 170 180
TVPGAGRGGQ GEEEDENARP LAESLLLAIA DLLFCPDFTV QNHRRNDVDS AEDVHSLDSC
190 200 210 220 230 240
EYIWEAGVGF AHSPQPNYIH DMNRMELLKL LLTCFSEAMY LPPSPESGST NPWVQFFCST
250 260 270 280 290 300
ENRHALPLFT SLLNTVCAYD PVGYGIPYNH LLFSDYREPL VEEAAQVLIV TLDHDSATST
310 320 330 340 350 360
SPTVDGTTTG TAMDDADPPG PENLFVNYLS RIHREEDFQF ILKGIARLLS NPLLQTYLPN
370 380 390 400 410 420
STKKIQFHQE LLVLFWKLCD FNKKFLFFVL KSSDVLDILV PILYFLNDAR ADQSRVGLMH
430 440 450 460 470 480
IGVFILLLLS GERNFGVRLN KPYSVRVPMD IPVFTGTHAD LLIVVFHKII TSGHQRLQPL
490 500 510 520 530 540
FDCLLTIVVN VSPYLKSLSM VTANKLLHLL EAFSTTWFLF SASQNHHLVF FLLEVFNNII
550 560 570 580 590 600
QYQFDGNSNL VYAIIRKRAV FHQLANLPTD PPSIHKALQR RRRTPEPLSR TGSQEGTSME
610 620 630 640 650 660
GSRPAAPAEP GTLKTSLVAT PGIDKLTEKS QVSEDGTLRS LEPESQQSSA ENSPSDGESS
670 680 690 700 710 720
QTWREQRRLS NASASGQWSP TSDWILSWKS KLPLQTIMRL LQVLVPQVEK ICIDKGLTDE
730 740 750 760 770 780
SEILRFLQHG TLVGLLPVPH PILIRKYQAN SGTAMWFRTY MWGVIYLRNV DPPIWYDTDV
KLFEIQRV