AiPD: Autoinhibited Protein Database

Gene name	Ccdc137
Protein name	Coiled-coil domain-containing protein 137
Names
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:67291
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-290 (Predicted disordered autoinhibitory region) PR

1-290 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8R0K4-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs225090707	6	N>S	No	EVA
rs219364582	9	L>P	No	EVA
rs239737146	10	V>A	No	EVA
rs215504432	25	G>A	No	EVA
rs232477375	26	R>W	No	EVA
rs250120389	29	Q>K	No	EVA
rs244685773	40	L>R	No	EVA
rs3402635673	65	F>C	No	EVA
rs3402862559	75	Q>K	No	EVA
rs3402891739	76	E>G	No	EVA
rs3389237227	90	A>T	No	EVA
rs3389218056	97	T>M	No	EVA
rs3413067182	105	E>K	No	EVA
rs3389218060	121	S>F	No	EVA
rs3389234540	129	M>I	No	EVA
rs3389221783	140	S>N	No	EVA
rs3389240993	144	A>T	No	EVA
rs3389226347	223	S>P	No	EVA
rs258658128	248	R>W	No	EVA
rs3389237175	276	Q>*	No	EVA

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q8R0K4

		Description
EC Number
Subcellular Localization	Chromosome
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
chromosome	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
fibrillar center	A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
nucleolus	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
No GO annotations for molecular function

Name	Definition
No GO annotations for biological process

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q6PK04	CCDC137	Coiled-coil domain-containing protein 137	Homo sapiens (Human)	PR